The basic reproductive number and particle-to-plaque ratio: comparison of these two parameters of viral infectivity

The COVID-19 pandemic has brought more widespread attention to the basic reproductive number (R(o)), an epidemiologic measurement. A lesser-known measure of virologic infectivity is the particle-to-plaque ratio (P:PFU). We suggest that comparison between the two parameters may assist in better under...

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Detalles Bibliográficos
Autores principales: McCormick, Winston, Mermel, Leonard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085655/
https://www.ncbi.nlm.nih.gov/pubmed/33931090
http://dx.doi.org/10.1186/s12985-021-01566-4
Descripción
Sumario:The COVID-19 pandemic has brought more widespread attention to the basic reproductive number (R(o)), an epidemiologic measurement. A lesser-known measure of virologic infectivity is the particle-to-plaque ratio (P:PFU). We suggest that comparison between the two parameters may assist in better understanding viral transmission dynamics.

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