The timing and design of stereotactic radiotherapy approaches as a part of neoadjuvant therapy in pancreatic cancer: Is it time for change?

Stereotactic Radiotherapy (SRT) over 5-15 days can be interdigitated without delaying chemotherapy. Bridging chemotherapy may allow for extended intervals to surgery, potentially improving sterilization of surgical margins and overall survival. SRT for pancreatic adenocarcinoma should not be limited...

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Detalles Bibliográficos
Autores principales: Ryckman, Jeffrey M., Reames, Bradley N., Klute, Kelsey A., Hall, William A., Baine, Michael J., Abdel-Wahab, May, Lin, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085778/
https://www.ncbi.nlm.nih.gov/pubmed/33981865
http://dx.doi.org/10.1016/j.ctro.2021.04.002
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author Ryckman, Jeffrey M.
Reames, Bradley N.
Klute, Kelsey A.
Hall, William A.
Baine, Michael J.
Abdel-Wahab, May
Lin, Chi
author_facet Ryckman, Jeffrey M.
Reames, Bradley N.
Klute, Kelsey A.
Hall, William A.
Baine, Michael J.
Abdel-Wahab, May
Lin, Chi
author_sort Ryckman, Jeffrey M.
collection PubMed
description Stereotactic Radiotherapy (SRT) over 5-15 days can be interdigitated without delaying chemotherapy. Bridging chemotherapy may allow for extended intervals to surgery, potentially improving sterilization of surgical margins and overall survival. SRT for pancreatic adenocarcinoma should not be limited to the tumor, and should consider hypofractionated approaches to regional nodes.
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spelling pubmed-80857782021-05-11 The timing and design of stereotactic radiotherapy approaches as a part of neoadjuvant therapy in pancreatic cancer: Is it time for change? Ryckman, Jeffrey M. Reames, Bradley N. Klute, Kelsey A. Hall, William A. Baine, Michael J. Abdel-Wahab, May Lin, Chi Clin Transl Radiat Oncol Review Article Stereotactic Radiotherapy (SRT) over 5-15 days can be interdigitated without delaying chemotherapy. Bridging chemotherapy may allow for extended intervals to surgery, potentially improving sterilization of surgical margins and overall survival. SRT for pancreatic adenocarcinoma should not be limited to the tumor, and should consider hypofractionated approaches to regional nodes. Elsevier 2021-04-19 /pmc/articles/PMC8085778/ /pubmed/33981865 http://dx.doi.org/10.1016/j.ctro.2021.04.002 Text en © 2021 The Author(s). Published by Elsevier B.V. on behalf of European Society for Radiotherapy and Oncology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Ryckman, Jeffrey M.
Reames, Bradley N.
Klute, Kelsey A.
Hall, William A.
Baine, Michael J.
Abdel-Wahab, May
Lin, Chi
The timing and design of stereotactic radiotherapy approaches as a part of neoadjuvant therapy in pancreatic cancer: Is it time for change?
title The timing and design of stereotactic radiotherapy approaches as a part of neoadjuvant therapy in pancreatic cancer: Is it time for change?
title_full The timing and design of stereotactic radiotherapy approaches as a part of neoadjuvant therapy in pancreatic cancer: Is it time for change?
title_fullStr The timing and design of stereotactic radiotherapy approaches as a part of neoadjuvant therapy in pancreatic cancer: Is it time for change?
title_full_unstemmed The timing and design of stereotactic radiotherapy approaches as a part of neoadjuvant therapy in pancreatic cancer: Is it time for change?
title_short The timing and design of stereotactic radiotherapy approaches as a part of neoadjuvant therapy in pancreatic cancer: Is it time for change?
title_sort timing and design of stereotactic radiotherapy approaches as a part of neoadjuvant therapy in pancreatic cancer: is it time for change?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085778/
https://www.ncbi.nlm.nih.gov/pubmed/33981865
http://dx.doi.org/10.1016/j.ctro.2021.04.002
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