A benzopyran with antiarrhythmic activity is an inhibitor of Kir3.1-containing potassium channels

Atrial fibrillation (AF) is the most commonly diagnosed cardiac arrhythmia and is associated with increased morbidity and mortality. Currently approved AF antiarrhythmic drugs have limited efficacy and/or carry the risk of ventricular proarrhythmia. The cardiac acetylcholine activated inwardly recti...

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Detalles Bibliográficos
Autores principales: Cui, Meng, Alhamshari, Yaser, Cantwell, Lucas, EI-Haou, Said, Eptaminitaki, Giasemi C., Chang, Mengmeng, Abou-Assali, Obada, Tan, Haozhou, Xu, Keman, Masotti, Meghan, Plant, Leigh D., Thakur, Ganesh A., Noujaim, Sami F., Milnes, James, Logothetis, Diomedes E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086025/
https://www.ncbi.nlm.nih.gov/pubmed/33713702
http://dx.doi.org/10.1016/j.jbc.2021.100535

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