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Multiple pathways coordinating reprogramming of endothelial cells into osteoblasts by BMP4

Cell type transition occurs during normal development and under pathological conditions. In prostate cancer bone metastasis, prostate cancer-secreted BMP4 induces endothelial cell-to-osteoblast (EC-to-OSB) transition. Such tumor-induced stromal reprogramming supports prostate cancer progression. We...

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Detalles Bibliográficos
Autores principales:	Yu, Guoyu, Shen, Pengfei, Lee, Yu-Chen, Pan, Jing, Song, Jian H., Pan, Tianhong, Lin, Song-Chang, Liang, Xin, Wang, Guocan, Panaretakis, Theocharis, Logothetis, Christopher J., Gallick, Gary E., Yu-Lee, Li-Yuan, Lin, Sue-Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086028/ https://www.ncbi.nlm.nih.gov/pubmed/33981975 http://dx.doi.org/10.1016/j.isci.2021.102388

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