Elevated APOBEC mutational signatures implicate chronic injury in etiology of an aggressive head-and-neck squamous cell carcinoma: a case report

BACKGROUND: Aggressive squamous cell carcinomas (SCCs) present frequently in the context of chronic skin injury occurring in patients with the congenital blistering disease recessive dystrophic epidermolysis bullosa. Recently, these cancers were shown to harbor mutation signatures associated with en...

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Detalles Bibliográficos
Autores principales: Patel, Jena, Breems, Nicoline Y. den, Tuluc, Madalina, Johnson, Jennifer, Curry, Joseph M, South, Andrew P., Cho, Raymond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086066/
https://www.ncbi.nlm.nih.gov/pubmed/33926553
http://dx.doi.org/10.1186/s13256-021-02685-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086066/
https://www.ncbi.nlm.nih.gov/pubmed/33926553
http://dx.doi.org/10.1186/s13256-021-02685-w

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