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Estimands in epigenome-wide association studies

BACKGROUND: In DNA methylation analyses like epigenome-wide association studies, effects in differentially methylated CpG sites are assessed. Two kinds of outcomes can be used for statistical analysis: Beta-values and M-values. M-values follow a normal distribution and help to detect differentially...

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Detalles Bibliográficos
Autores principales:	Kruppa, Jochen, Sieg, Miriam, Richter, Gesa, Pohrt, Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086103/ https://www.ncbi.nlm.nih.gov/pubmed/33926513 http://dx.doi.org/10.1186/s13148-021-01083-9

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