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TCF7 is not essential for glucose homeostasis in mice

OBJECTIVE: Glucose-dependent insulinotropic polypeptide (GIP) and Glucagon-like peptide-1 (GLP-1) are incretin hormones that exert overlapping yet distinct actions on islet β-cells. We recently observed that GIP, but not GLP-1, upregulated islet expression of Transcription Factor 7 (TCF7), a gene ex...

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Detalles Bibliográficos
Autores principales:	Kaur, Kiran Deep, Wong, Chi Kin, Baggio, Laurie L., Beaudry, Jacqueline L., Fuchs, Shai, Panaro, Brandon L., Matthews, Dianne, Cao, Xiemin, Drucker, Daniel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086146/ https://www.ncbi.nlm.nih.gov/pubmed/33741532 http://dx.doi.org/10.1016/j.molmet.2021.101213

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