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Effect of the glycine-rich domain in GAREM2 on its unique subcellular localization upon EGF stimulation
BACKGROUND: In mammals, there are two subtypes of Grb2-associated regulator of Erk/MAPK (GAREM), an adaptor protein that functions downstream of the cell growth factor receptor. GAREM1 is ubiquitously expressed, whereas GAREM2 is mainly expressed in the brain. However, the precise mechanism of the t...
Autores principales: | Nishino, Tasuku, Oshika, Tsuyoshi, Kyan, Moriatsu, Konishi, Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086153/ https://www.ncbi.nlm.nih.gov/pubmed/33931009 http://dx.doi.org/10.1186/s11658-021-00260-1 |
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