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The TRPM3 ion channel mediates nociception but not itch evoked by endogenous pruritogenic mediators
During the molecular transduction of itch, the stimulation of pruriceptors on sensory fibers leads to the activation or sensitization of ion channels, which results in a consequent depolarization of the neurons. These ion channels mostly belong to the transient receptor potential (TRP) channels, whi...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086171/ https://www.ncbi.nlm.nih.gov/pubmed/33130130 http://dx.doi.org/10.1016/j.bcp.2020.114310 |