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The TRPM3 ion channel mediates nociception but not itch evoked by endogenous pruritogenic mediators

During the molecular transduction of itch, the stimulation of pruriceptors on sensory fibers leads to the activation or sensitization of ion channels, which results in a consequent depolarization of the neurons. These ion channels mostly belong to the transient receptor potential (TRP) channels, whi...

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Detalles Bibliográficos
Autores principales: Kelemen, Balázs, Pinto, Silvia, Kim, Nawoo, Lisztes, Erika, Hanyicska, Martin, Vládar, Anita, Oláh, Attila, Pénzes, Zsófia, Shu, Brian, Vriens, Joris, Bíró, Tamás, Rohács, Tibor, Voets, Thomas, Tóth, Balázs István
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086171/
https://www.ncbi.nlm.nih.gov/pubmed/33130130
http://dx.doi.org/10.1016/j.bcp.2020.114310