Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana

The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi salt...

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Autores principales: Modikwe, Gorata, Manoharan, Lokeshwaran, Mabutho, Gomolemo, Lebani, Kebaneilwe, Lebogang, Lesedi, Zhou, Nerve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Genome Sequences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086208/
https://www.ncbi.nlm.nih.gov/pubmed/33927034
http://dx.doi.org/10.1128/MRA.00175-21
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author Modikwe, Gorata
Manoharan, Lokeshwaran
Mabutho, Gomolemo
Lebani, Kebaneilwe
Lebogang, Lesedi
Zhou, Nerve
author_facet Modikwe, Gorata
Manoharan, Lokeshwaran
Mabutho, Gomolemo
Lebani, Kebaneilwe
Lebogang, Lesedi
Zhou, Nerve
author_sort Modikwe, Gorata
collection PubMed
description The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi saltpans in Botswana. Bioinformatic analyses revealed 12 putative secondary metabolite biosynthetic gene clusters important for genome-guided drug discovery studies.
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spelling pubmed-80862082021-05-04 Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana Modikwe, Gorata Manoharan, Lokeshwaran Mabutho, Gomolemo Lebani, Kebaneilwe Lebogang, Lesedi Zhou, Nerve Microbiol Resour Announc Genome Sequences The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi saltpans in Botswana. Bioinformatic analyses revealed 12 putative secondary metabolite biosynthetic gene clusters important for genome-guided drug discovery studies. American Society for Microbiology 2021-04-29 /pmc/articles/PMC8086208/ /pubmed/33927034 http://dx.doi.org/10.1128/MRA.00175-21 Text en Copyright © 2021 Modikwe et al. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Genome Sequences
Modikwe, Gorata
Manoharan, Lokeshwaran
Mabutho, Gomolemo
Lebani, Kebaneilwe
Lebogang, Lesedi
Zhou, Nerve
Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana
title Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana
title_full Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana
title_fullStr Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana
title_full_unstemmed Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana
title_short Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana
title_sort complete genome sequence of an antimicrobial-producing bacillus velezensis sam8h1 isolate from the makgadikgadi saltpans of botswana
topic Genome Sequences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086208/
https://www.ncbi.nlm.nih.gov/pubmed/33927034
http://dx.doi.org/10.1128/MRA.00175-21
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