Closed and High-Quality Bacterial Genome Sequences of the Oligo-Mouse-Microbiota Community

The Oligo-Mouse-Microbiota (OMM(12)) gnotobiotic murine model is an increasingly popular model in microbiota studies. However, following Illumina and PacBio sequencing, the genomes of the 12 strains could not be closed. Here, we used genomic chromosome conformation capture (Hi-C) data to reorganize,...

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Detalles Bibliográficos
Autores principales: Lamy-Besnier, Quentin, Koszul, Romain, Debarbieux, Laurent, Marbouty, Martial
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Genome Sequences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086220/
https://www.ncbi.nlm.nih.gov/pubmed/33927045
http://dx.doi.org/10.1128/MRA.01396-20
Descripción
Sumario:The Oligo-Mouse-Microbiota (OMM(12)) gnotobiotic murine model is an increasingly popular model in microbiota studies. However, following Illumina and PacBio sequencing, the genomes of the 12 strains could not be closed. Here, we used genomic chromosome conformation capture (Hi-C) data to reorganize, close, and improve the quality of these 12 genomes.

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