CD36 polymorphisms and the age of disease onset in patients with pathogenic variants within the mutation cluster region of APC

BACKGROUND: Familial adenomatous polyposis (FAP) is an autosomal dominant condition that predisposes patients to colorectal cancer. FAP is the result of a loss of APC function due to germline pathogenic variants disrupting gene expression. Genotype-phenotype correlations are described for FAP. For e...

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Detalles Bibliográficos
Autores principales: Connor, T, McPhillips, M, Hipwell, M, Ziolkowski, A, Oldmeadow, C, Clapham, M, Pockney, PG, Lis, E, Banasiewicz, T, Pławski, A, Scott, RJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086281/
https://www.ncbi.nlm.nih.gov/pubmed/33926505
http://dx.doi.org/10.1186/s13053-021-00183-0

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