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KLF5-induced BBOX1-AS1 contributes to cell malignant phenotypes in non-small cell lung cancer via sponging miR-27a-5p to up-regulate MELK and activate FAK signaling pathway

BACKGROUND: Non-small cell lung cancer (NSCLC) is a major histological subtype of lung cancer with high mortality and morbidity. A substantial amount of evidence demonstrates long non-coding RNAs (lncRNA) as critical regulators in tumorigeneis and malignant progression of human cancers. The oncogeni...

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Detalles Bibliográficos
Autores principales: Shi, Jiang, Yang, Chao, An, Jinlu, Hao, Dexun, Liu, Cong, Liu, Jumin, Sun, Jing, Jiang, Junguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086369/
https://www.ncbi.nlm.nih.gov/pubmed/33931086
http://dx.doi.org/10.1186/s13046-021-01943-5

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