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Prognostic value of daytime heart rate, blood pressure, their products and quotients in chronic heart failure

BACKGROUND: Chronic heart failure (CHF) is an important epidemiological and therapeuthic issue with poor prognosis. The aim of the study was to estimate the prognostic value of daytime heart rate (HR), blood pressure (BP), their products and quotients in patients with CHF. METHODS: The study include...

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Autores principales: Kowalczys, Anna, Bohdan, Michal, Gruchala, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Via Medica 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086683/
https://www.ncbi.nlm.nih.gov/pubmed/29131282
http://dx.doi.org/10.5603/CJ.a2017.0130
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author Kowalczys, Anna
Bohdan, Michal
Gruchala, Marcin
author_facet Kowalczys, Anna
Bohdan, Michal
Gruchala, Marcin
author_sort Kowalczys, Anna
collection PubMed
description BACKGROUND: Chronic heart failure (CHF) is an important epidemiological and therapeuthic issue with poor prognosis. The aim of the study was to estimate the prognostic value of daytime heart rate (HR), blood pressure (BP), their products and quotients in patients with CHF. METHODS: The study included 80 stable patients with CHF and reduced left ventricular ejection fraction (LVEF ≤ 35%). Physical examination, laboratory blood tests, electrocardiogram, chest X-ray, echocardiography, 6-minute walk test, telemetry monitoring and BP measurements were performed in all participants. We estimated mean daytime: BP, HR, their products and quotients. The follow-up period was 6 months. Major adverse cardiac events (MACE) included: death, cardiovascular death, hospitalization due to CHF exacerbation. RESULTS: The analysis involved all recruited patients with CHF (91% men) aged 59 ± 12 years, in New York Heart Association class 2.15 ± 0.57 and reduced LVEF (mean LVEF: 23 ± 6%). The 3-month and 6-month mortality rates were 4% and 6%, respectively. There was a significant correlation between diastolic blood pressure (DBP), all-cause mortality (p = 0.048) and CHF decompensation (p = 0.0004) after 3-month observation period. No relationship was found between HR or systolic blood pressure (SBP) and MACE. Both higher SBP × HR and DBP × HR products were related to lower risk of heart failure exacerbations during 6-month follow-up. None of the analyzed products or ratios had an impact on mortality in this study group. CONCLUSIONS: Diastolic blood pressure, SBP × HR and DBP × HR products may be useful in subsequent heart failure exacerbation risk stratification. Moreover, DBP value may predict short-term mortality in patients with CHF.
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spelling pubmed-80866832021-05-10 Prognostic value of daytime heart rate, blood pressure, their products and quotients in chronic heart failure Kowalczys, Anna Bohdan, Michal Gruchala, Marcin Cardiol J Clinical Cardiology BACKGROUND: Chronic heart failure (CHF) is an important epidemiological and therapeuthic issue with poor prognosis. The aim of the study was to estimate the prognostic value of daytime heart rate (HR), blood pressure (BP), their products and quotients in patients with CHF. METHODS: The study included 80 stable patients with CHF and reduced left ventricular ejection fraction (LVEF ≤ 35%). Physical examination, laboratory blood tests, electrocardiogram, chest X-ray, echocardiography, 6-minute walk test, telemetry monitoring and BP measurements were performed in all participants. We estimated mean daytime: BP, HR, their products and quotients. The follow-up period was 6 months. Major adverse cardiac events (MACE) included: death, cardiovascular death, hospitalization due to CHF exacerbation. RESULTS: The analysis involved all recruited patients with CHF (91% men) aged 59 ± 12 years, in New York Heart Association class 2.15 ± 0.57 and reduced LVEF (mean LVEF: 23 ± 6%). The 3-month and 6-month mortality rates were 4% and 6%, respectively. There was a significant correlation between diastolic blood pressure (DBP), all-cause mortality (p = 0.048) and CHF decompensation (p = 0.0004) after 3-month observation period. No relationship was found between HR or systolic blood pressure (SBP) and MACE. Both higher SBP × HR and DBP × HR products were related to lower risk of heart failure exacerbations during 6-month follow-up. None of the analyzed products or ratios had an impact on mortality in this study group. CONCLUSIONS: Diastolic blood pressure, SBP × HR and DBP × HR products may be useful in subsequent heart failure exacerbation risk stratification. Moreover, DBP value may predict short-term mortality in patients with CHF. Via Medica 2019-03-14 /pmc/articles/PMC8086683/ /pubmed/29131282 http://dx.doi.org/10.5603/CJ.a2017.0130 Text en Copyright © 2019 Via Medica https://creativecommons.org/licenses/by-nc-nd/4.0/This article is available in open access under Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
spellingShingle Clinical Cardiology
Kowalczys, Anna
Bohdan, Michal
Gruchala, Marcin
Prognostic value of daytime heart rate, blood pressure, their products and quotients in chronic heart failure
title Prognostic value of daytime heart rate, blood pressure, their products and quotients in chronic heart failure
title_full Prognostic value of daytime heart rate, blood pressure, their products and quotients in chronic heart failure
title_fullStr Prognostic value of daytime heart rate, blood pressure, their products and quotients in chronic heart failure
title_full_unstemmed Prognostic value of daytime heart rate, blood pressure, their products and quotients in chronic heart failure
title_short Prognostic value of daytime heart rate, blood pressure, their products and quotients in chronic heart failure
title_sort prognostic value of daytime heart rate, blood pressure, their products and quotients in chronic heart failure
topic Clinical Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086683/
https://www.ncbi.nlm.nih.gov/pubmed/29131282
http://dx.doi.org/10.5603/CJ.a2017.0130
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