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Automated Quantitative Analysis of ex vivo Blood-Brain Barrier Permeability Using Intellesis Machine-Learning
BACKGROUND: An increase in blood brain barrier permeability commonly precedes neuro-inflammation and cognitive impairment in models of dementia. Common methods to estimate capillary permeability have potential confounders, or require laborious and subjective semi-manual analysis. NEW METHOD: Here we...
Autores principales: | Nesbit, Michael, Mamo, John C., Majimbi, Maimuna, Lam, Virginie, Takechi, Ryusuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086794/ https://www.ncbi.nlm.nih.gov/pubmed/33935625 http://dx.doi.org/10.3389/fnins.2021.617221 |
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