Assessing the Association of Mitochondrial Function and Inflammasome Activation in Murine Macrophages Exposed to Select Mitotoxic Tri-Organotin Compounds

BACKGROUND: Mitochondrial function is implicated as a target of environmental toxicants and found in disease or injury models, contributing to acute and chronic inflammation. One mechanism by which mitochondrial damage can propagate inflammation is via activation of the nucleotide-binding oligomeriz...

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Detalles Bibliográficos
Autores principales: Childers, Gabrielle M., Perry, Caroline A., Blachut, Barbara, Martin, Negin, Bortner, Carl D., Sieber, Stella, Li, Jian-Liang, Fessler, Michael B., Harry, G. Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086801/
https://www.ncbi.nlm.nih.gov/pubmed/33929904
http://dx.doi.org/10.1289/EHP8314

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