CURB-65 as a predictor of 30-day mortality in patients hospitalized with COVID-19 in Ecuador: COVID-EC study()

OBJECTIVE: This article aims to assess the utility of CURB-65 in predicting 30-day mortality in adult patients hospitalized with COVID-19. METHODS: This work is a cohort study conducted between March 1 and April 30, 2020 in Ecuador. RESULTS: A total of 247 patients were included (mean age 60 ± 14 ye...

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Detalles Bibliográficos
Autores principales: Carriel, J., Muñoz-Jaramillo, R., Bolaños-Ladinez, O., Heredia-Villacreses, F., Menéndez-Sanchón, J., Martin-Delgado, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). 2022
Materias:
Brief Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086802/
https://www.ncbi.nlm.nih.gov/pubmed/34996587
http://dx.doi.org/10.1016/j.rceng.2020.10.006
Descripción
Sumario:OBJECTIVE: This article aims to assess the utility of CURB-65 in predicting 30-day mortality in adult patients hospitalized with COVID-19. METHODS: This work is a cohort study conducted between March 1 and April 30, 2020 in Ecuador. RESULTS: A total of 247 patients were included (mean age 60 ± 14 years, 70% men, overall mortality 41.3%). Patients with CURB-65 ≥ 2 had a higher mortality rate (57 vs. 17%, p < .001) that was associated with other markers of risk: advanced age, hypertension, overweight/obesity, kidney failure, hypoxemia, requirement for mechanical ventilation, or onset of respiratory distress. CONCLUSIONS: CURB-65  ≥ 2 was associated with higher 30-day mortality on the univariate (Kaplan–Meier estimator) and multivariate (Cox regression) analysis.

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