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Refining pairwise sequence alignments of membrane proteins by the incorporation of anchors
The alignment of primary sequences is a fundamental step in the analysis of protein structure, function, and evolution, and in the generation of homology-based models. Integral membrane proteins pose a significant challenge for such sequence alignment approaches, because their evolutionary relations...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087094/ https://www.ncbi.nlm.nih.gov/pubmed/33930031 http://dx.doi.org/10.1371/journal.pone.0239881 |