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Benzo[a]pyrene Cytotoxicity Tolerance in Testicular Sertoli Cells Involves Aryl-hydrocarbon Receptor and Cytochrome P450 1A1 Expression Deficiencies

Benzo[a]pyrene (B[a]P) is a potent carcinogen and is classified as an endocrine-disrupting chemical. In mammalian testes, Sertoli cells support spermatogenesis. Therefore, if these cells are negatively affected by exposure to xenotoxic chemicals, spermatogenesis can be seriously disrupted. In this c...

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Detalles Bibliográficos
Autores principales:	Kim, Jin-Tac, Park, Ji-Eun, Lee, Seung-Jin, Yu, Wook-Joon, Lee, Hye-Jeong, Kim, Jong-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society of Developmental Biology 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087263/ https://www.ncbi.nlm.nih.gov/pubmed/33977171 http://dx.doi.org/10.12717/DR.2021.25.1.15

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