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Polygenic Risk Score of Longevity Predicts Longer Survival Across an Age Continuum

Studying the genome of centenarians may give insights into the molecular mechanisms underlying extreme human longevity and the escape of age-related diseases. Here, we set out to construct polygenic risk scores (PRSs) for longevity and to investigate the functions of longevity-associated variants. U...

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Detalles Bibliográficos
Autores principales:	Tesi, Niccolo’, van der Lee, Sven J, Hulsman, Marc, Jansen, Iris E, Stringa, Najada, van Schoor, Natasja M, Scheltens, Philip, van der Flier, Wiesje M, Huisman, Martijn, Reinders, Marcel J T, Holstege, Henne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	THE JOURNAL OF GERONTOLOGY: Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087277/ https://www.ncbi.nlm.nih.gov/pubmed/33216869 http://dx.doi.org/10.1093/gerona/glaa289

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