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Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor
Necrotizing sialometaplasia (NS) is a benign, self-limiting inflammatory entity that mainly affects the minor salivary glands located in the hard palate. Classically, NS is characterized as a nodule that evolves to a central ulcer. The most widely recognized triggering factor is an ischemic event. T...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hospital Universitário da Universidade de São Paulo
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087373/ https://www.ncbi.nlm.nih.gov/pubmed/33968823 http://dx.doi.org/10.4322/acr.2021.244 |
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author | Fernandes, Patrícia Maria Pedroso, Erika Graf Santos-Silva, Alan Roger Vargas, Pablo Agustin Lopes, Márcio Ajudarte |
author_facet | Fernandes, Patrícia Maria Pedroso, Erika Graf Santos-Silva, Alan Roger Vargas, Pablo Agustin Lopes, Márcio Ajudarte |
author_sort | Fernandes, Patrícia Maria |
collection | PubMed |
description | Necrotizing sialometaplasia (NS) is a benign, self-limiting inflammatory entity that mainly affects the minor salivary glands located in the hard palate. Classically, NS is characterized as a nodule that evolves to a central ulcer. The most widely recognized triggering factor is an ischemic event. The diagnosis becomes a challenge in non-ulcerated NS cases which is essential to rule out the possibility of salivary gland tumors, especially the malignant ones. Here, we presented a case of a 32-year-old male patient with a 1-month complaint of a painful, slightly elevated erythematous area on the hard palate. Incisional biopsy was performed, and NS was diagnosed based on histopathological and immunohistochemical analyses. Clinicians should be aware of and consider NS as a differential diagnosis of minor salivary gland tumors, particularly when it presents as a non-ulcerated clinical aspect. |
format | Online Article Text |
id | pubmed-8087373 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hospital Universitário da Universidade de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-80873732021-05-07 Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor Fernandes, Patrícia Maria Pedroso, Erika Graf Santos-Silva, Alan Roger Vargas, Pablo Agustin Lopes, Márcio Ajudarte Autops Case Rep Clinical Case Report Necrotizing sialometaplasia (NS) is a benign, self-limiting inflammatory entity that mainly affects the minor salivary glands located in the hard palate. Classically, NS is characterized as a nodule that evolves to a central ulcer. The most widely recognized triggering factor is an ischemic event. The diagnosis becomes a challenge in non-ulcerated NS cases which is essential to rule out the possibility of salivary gland tumors, especially the malignant ones. Here, we presented a case of a 32-year-old male patient with a 1-month complaint of a painful, slightly elevated erythematous area on the hard palate. Incisional biopsy was performed, and NS was diagnosed based on histopathological and immunohistochemical analyses. Clinicians should be aware of and consider NS as a differential diagnosis of minor salivary gland tumors, particularly when it presents as a non-ulcerated clinical aspect. Hospital Universitário da Universidade de São Paulo 2021-04-19 /pmc/articles/PMC8087373/ /pubmed/33968823 http://dx.doi.org/10.4322/acr.2021.244 Text en Copyright: © 2021 The Authors. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Case Report Fernandes, Patrícia Maria Pedroso, Erika Graf Santos-Silva, Alan Roger Vargas, Pablo Agustin Lopes, Márcio Ajudarte Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor |
title | Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor |
title_full | Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor |
title_fullStr | Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor |
title_full_unstemmed | Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor |
title_short | Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor |
title_sort | non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor |
topic | Clinical Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087373/ https://www.ncbi.nlm.nih.gov/pubmed/33968823 http://dx.doi.org/10.4322/acr.2021.244 |
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