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Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor

Necrotizing sialometaplasia (NS) is a benign, self-limiting inflammatory entity that mainly affects the minor salivary glands located in the hard palate. Classically, NS is characterized as a nodule that evolves to a central ulcer. The most widely recognized triggering factor is an ischemic event. T...

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Autores principales: Fernandes, Patrícia Maria, Pedroso, Erika Graf, Santos-Silva, Alan Roger, Vargas, Pablo Agustin, Lopes, Márcio Ajudarte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital Universitário da Universidade de São Paulo 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087373/
https://www.ncbi.nlm.nih.gov/pubmed/33968823
http://dx.doi.org/10.4322/acr.2021.244
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author Fernandes, Patrícia Maria
Pedroso, Erika Graf
Santos-Silva, Alan Roger
Vargas, Pablo Agustin
Lopes, Márcio Ajudarte
author_facet Fernandes, Patrícia Maria
Pedroso, Erika Graf
Santos-Silva, Alan Roger
Vargas, Pablo Agustin
Lopes, Márcio Ajudarte
author_sort Fernandes, Patrícia Maria
collection PubMed
description Necrotizing sialometaplasia (NS) is a benign, self-limiting inflammatory entity that mainly affects the minor salivary glands located in the hard palate. Classically, NS is characterized as a nodule that evolves to a central ulcer. The most widely recognized triggering factor is an ischemic event. The diagnosis becomes a challenge in non-ulcerated NS cases which is essential to rule out the possibility of salivary gland tumors, especially the malignant ones. Here, we presented a case of a 32-year-old male patient with a 1-month complaint of a painful, slightly elevated erythematous area on the hard palate. Incisional biopsy was performed, and NS was diagnosed based on histopathological and immunohistochemical analyses. Clinicians should be aware of and consider NS as a differential diagnosis of minor salivary gland tumors, particularly when it presents as a non-ulcerated clinical aspect.
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spelling pubmed-80873732021-05-07 Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor Fernandes, Patrícia Maria Pedroso, Erika Graf Santos-Silva, Alan Roger Vargas, Pablo Agustin Lopes, Márcio Ajudarte Autops Case Rep Clinical Case Report Necrotizing sialometaplasia (NS) is a benign, self-limiting inflammatory entity that mainly affects the minor salivary glands located in the hard palate. Classically, NS is characterized as a nodule that evolves to a central ulcer. The most widely recognized triggering factor is an ischemic event. The diagnosis becomes a challenge in non-ulcerated NS cases which is essential to rule out the possibility of salivary gland tumors, especially the malignant ones. Here, we presented a case of a 32-year-old male patient with a 1-month complaint of a painful, slightly elevated erythematous area on the hard palate. Incisional biopsy was performed, and NS was diagnosed based on histopathological and immunohistochemical analyses. Clinicians should be aware of and consider NS as a differential diagnosis of minor salivary gland tumors, particularly when it presents as a non-ulcerated clinical aspect. Hospital Universitário da Universidade de São Paulo 2021-04-19 /pmc/articles/PMC8087373/ /pubmed/33968823 http://dx.doi.org/10.4322/acr.2021.244 Text en Copyright: © 2021 The Authors. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Case Report
Fernandes, Patrícia Maria
Pedroso, Erika Graf
Santos-Silva, Alan Roger
Vargas, Pablo Agustin
Lopes, Márcio Ajudarte
Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor
title Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor
title_full Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor
title_fullStr Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor
title_full_unstemmed Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor
title_short Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor
title_sort non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor
topic Clinical Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087373/
https://www.ncbi.nlm.nih.gov/pubmed/33968823
http://dx.doi.org/10.4322/acr.2021.244
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