Primary diffuse large B-cell lymphoma of the CNS, with a “Lymphomatosis cerebri” pattern

We describe an unusual case of lymphomatosis cerebri in a middle-aged lady presenting with rapid-onset dementia. The lymphomatous infiltrate, instead of forming mass lesions, percolated throughout the brain parenchyma, which is often missed on a stereotactic biopsy and hence warrants caution and awa...

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Autores principales: Thirunavukkarasu, Balamurugan, Gupta, Kirti, Shree, Ritu, Prabhakar, Anuj, Kapila, Aastha Takkar, Lal, Vivek, Radotra, Bishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital Universitário da Universidade de São Paulo 2021
Materias:
Autopsy Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087396/
https://www.ncbi.nlm.nih.gov/pubmed/33968825
http://dx.doi.org/10.4322/acr.2021.250
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author Thirunavukkarasu, Balamurugan
Gupta, Kirti
Shree, Ritu
Prabhakar, Anuj
Kapila, Aastha Takkar
Lal, Vivek
Radotra, Bishan
author_facet Thirunavukkarasu, Balamurugan
Gupta, Kirti
Shree, Ritu
Prabhakar, Anuj
Kapila, Aastha Takkar
Lal, Vivek
Radotra, Bishan
author_sort Thirunavukkarasu, Balamurugan
collection PubMed
description We describe an unusual case of lymphomatosis cerebri in a middle-aged lady presenting with rapid-onset dementia. The lymphomatous infiltrate, instead of forming mass lesions, percolated throughout the brain parenchyma, which is often missed on a stereotactic biopsy and hence warrants caution and awareness about this entity. The nonspecific symptoms at presentation and a variable picture at imaging make this entity diagnostically challenging.
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spelling pubmed-80873962021-05-07 Primary diffuse large B-cell lymphoma of the CNS, with a “Lymphomatosis cerebri” pattern Thirunavukkarasu, Balamurugan Gupta, Kirti Shree, Ritu Prabhakar, Anuj Kapila, Aastha Takkar Lal, Vivek Radotra, Bishan Autops Case Rep Autopsy Case Report We describe an unusual case of lymphomatosis cerebri in a middle-aged lady presenting with rapid-onset dementia. The lymphomatous infiltrate, instead of forming mass lesions, percolated throughout the brain parenchyma, which is often missed on a stereotactic biopsy and hence warrants caution and awareness about this entity. The nonspecific symptoms at presentation and a variable picture at imaging make this entity diagnostically challenging. Hospital Universitário da Universidade de São Paulo 2021-04-23 /pmc/articles/PMC8087396/ /pubmed/33968825 http://dx.doi.org/10.4322/acr.2021.250 Text en Copyright: © 2021 The Authors. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Autopsy Case Report
Thirunavukkarasu, Balamurugan
Gupta, Kirti
Shree, Ritu
Prabhakar, Anuj
Kapila, Aastha Takkar
Lal, Vivek
Radotra, Bishan
Primary diffuse large B-cell lymphoma of the CNS, with a “Lymphomatosis cerebri” pattern
title Primary diffuse large B-cell lymphoma of the CNS, with a “Lymphomatosis cerebri” pattern
title_full Primary diffuse large B-cell lymphoma of the CNS, with a “Lymphomatosis cerebri” pattern
title_fullStr Primary diffuse large B-cell lymphoma of the CNS, with a “Lymphomatosis cerebri” pattern
title_full_unstemmed Primary diffuse large B-cell lymphoma of the CNS, with a “Lymphomatosis cerebri” pattern
title_short Primary diffuse large B-cell lymphoma of the CNS, with a “Lymphomatosis cerebri” pattern
title_sort primary diffuse large b-cell lymphoma of the cns, with a “lymphomatosis cerebri” pattern
topic Autopsy Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087396/
https://www.ncbi.nlm.nih.gov/pubmed/33968825
http://dx.doi.org/10.4322/acr.2021.250
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