Potent programmable antiviral against dengue virus in primary human cells by Cas13b RNP with short spacer and delivery by VLP

With sequencing as a standard frontline protocol to identify emerging viruses such Zika virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), direct utilization of sequence data to program antivirals against the viruses could accelerate drug development to treat their infections. C...

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Detalles Bibliográficos
Autores principales: Singsuksawat, Ekapot, Onnome, Suppachoke, Posiri, Pratsaneeyaporn, Suphatrakul, Amporn, Srisuk, Nittaya, Nantachokchawapan, Rapirat, Praneechit, Hansa, Sae-kow, Chutimon, Chidpratum, Pala, Sa-ngiamsuntorn, Khanit, Hongeng, Suradej, Avirutnan, Panisadee, Duangchinda, Thaneeya, Siridechadilok, Bunpote
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087611/
https://www.ncbi.nlm.nih.gov/pubmed/33969146
http://dx.doi.org/10.1016/j.omtm.2021.04.014

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