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EGFR-ERK induced activation of GRHL1 promotes cell cycle progression by up-regulating cell cycle related genes in lung cancer

Grainyhead-like 1 (GRHL1) is a transcription factor involved in embryonic development. However, little is known about the biological functions of GRHL1 in cancer. In this study, we found that GRHL1 was upregulated in non-small cell lung cancer (NSCLC) and correlated with poor survival of patients. G...

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Detalles Bibliográficos
Autores principales:	He, Yiming, Gan, Mingxi, Wang, Yanan, Huang, Tong, Wang, Jianbin, Han, Tianyu, Yu, Bentong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087693/ https://www.ncbi.nlm.nih.gov/pubmed/33931584 http://dx.doi.org/10.1038/s41419-021-03721-9

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