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Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia

Electrical activity in the heart exhibits 24-hour rhythmicity, and potentially fatal arrhythmias are more likely to occur at specific times of day. Here, we demonstrate that circadian clocks within the brain and heart set daily rhythms in sinoatrial (SA) and atrioventricular (AV) node activity, and...

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Detalles Bibliográficos
Autores principales: Hayter, Edward A., Wehrens, Sophie M. T., Van Dongen, Hans P. A., Stangherlin, Alessandra, Gaddameedhi, Shobhan, Crooks, Elena, Barron, Nichola J., Venetucci, Luigi A., O’Neill, John S., Brown, Timothy M., Skene, Debra J., Trafford, Andrew W., Bechtold, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087694/
https://www.ncbi.nlm.nih.gov/pubmed/33931651
http://dx.doi.org/10.1038/s41467-021-22788-8