Whole-genome sequencing reveals rare off-target mutations in CRISPR/Cas9-edited grapevine

The CRISPR (clustered regularly interspaced short palindromic repeats)-associated protein 9 (Cas9) system is a powerful tool for targeted genome editing, with applications that include plant biotechnology and functional genomics research. However, the specificity of Cas9 targeting is poorly investig...

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Detalles Bibliográficos
Autores principales: Wang, Xianhang, Tu, Mingxing, Wang, Ya, Yin, Wuchen, Zhang, Yu, Wu, Hongsong, Gu, Yincong, Li, Zhi, Xi, Zhumei, Wang, Xiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087786/
https://www.ncbi.nlm.nih.gov/pubmed/33931634
http://dx.doi.org/10.1038/s41438-021-00549-4

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