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Parallel G-quadruplexes recruit the HSV-1 transcription factor ICP4 to promote viral transcription in herpes virus-infected human cells

G-quadruplexes (G4s) are four-stranded nucleic acid structures abundant at gene promoters. They can adopt several distinctive conformations. G4s have been shown to form in the herpes simplex virus-1 (HSV-1) genome during its viral cycle. Here by cross-linking/pull-down assay we identified ICP4, the...

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Detalles Bibliográficos
Autores principales:	Frasson, Ilaria, Soldà, Paola, Nadai, Matteo, Lago, Sara, Richter, Sara N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087788/ https://www.ncbi.nlm.nih.gov/pubmed/33931711 http://dx.doi.org/10.1038/s42003-021-02035-y

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