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The metastasis suppressor protein NM23-H1 modulates the PI3K-AKT axis through interaction with the p110α catalytic subunit

The PI3K pathway is one of the most deregulated pathways in cancer, which is predominantly due to gain of function mutations or altered expression of the PI3KCA gene. This is codified by what is seen for the class I PI3K catalytic subunit p110α, a common feature of many cancers. The metastasis suppr...

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Detalles Bibliográficos
Autores principales:	Pennino, Francesco Paolo, Murakami, Masanao, Zollo, Massimo, Robertson, Erle S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087825/ https://www.ncbi.nlm.nih.gov/pubmed/33931587 http://dx.doi.org/10.1038/s41389-021-00326-x

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