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Copy number and transcriptome alterations associated with metastatic lesion response to treatment in colorectal cancer

BACKGROUND: Therapeutic resistance is the main cause of death in metastatic colorectal cancer. To investigate genomic plasticity, most specifically of metastatic lesions, associated with response to first‐line systemic therapy, we collected longitudinal liver metastatic samples and characterized the...

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Detalles Bibliográficos
Autores principales: Gambaro, Karen, Marques, Maud, McNamara, Suzan, Couetoux du Tertre, Mathilde, Diaz, Zuanel, Hoffert, Cyrla, Srivastava, Archana, Hébert, Steven, Samson, Benoit, Lespérance, Bernard, Ko, Yoo‐Joung, Dalfen, Richard, St‐Hilaire, Eve, Sideris, Lucas, Couture, Felix, Burkes, Ronald, Harb, Mohammed, Camlioglu, Errol, Gologan, Adrian, Pelsser, Vincent, Constantin, André, Greenwood, Celia M.T., Tejpar, Sabine, Kavan, Petr, Kleinman, Claudia L., Batist, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087915/
https://www.ncbi.nlm.nih.gov/pubmed/33931971
http://dx.doi.org/10.1002/ctm2.401

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