Trisomy 21 as a Risk Factor for Severe Illness in COVID-19: Report of two Cases

COVID-19 leads to mild symptoms within the majority of infected patients, but can cause severe multiple organ failure and death. There is only limited information regarding the consequences of this new emerging infection with congenital disorders. According to the previous studies, many people with...

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Autores principales: Babamahmoodi, Abdolreza, Moniri, Afshin, Sadr, Makan, Poorhosseini, Seyed Mohammad, Rezaei, Mitra, Marjani, Majid, Velayati, Ali Akbar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Research Institute of Tuberculosis and Lung Disease 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088146/
https://www.ncbi.nlm.nih.gov/pubmed/33959180
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author Babamahmoodi, Abdolreza
Moniri, Afshin
Sadr, Makan
Poorhosseini, Seyed Mohammad
Rezaei, Mitra
Marjani, Majid
Velayati, Ali Akbar
author_facet Babamahmoodi, Abdolreza
Moniri, Afshin
Sadr, Makan
Poorhosseini, Seyed Mohammad
Rezaei, Mitra
Marjani, Majid
Velayati, Ali Akbar
author_sort Babamahmoodi, Abdolreza
collection PubMed
description COVID-19 leads to mild symptoms within the majority of infected patients, but can cause severe multiple organ failure and death. There is only limited information regarding the consequences of this new emerging infection with congenital disorders. According to the previous studies, many people with Down syndrome are considered high risk for complications related to respiratory diseases. We report two trisomy 21 patients who suffered from COVID-19 and summarize the early experience with COVID-19 and Down syndrome. The course of the disease was severe in these two cases, and our concern is close monitoring of the patients with Down syndrome for early signs of COVID-19.
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spelling pubmed-80881462021-05-05 Trisomy 21 as a Risk Factor for Severe Illness in COVID-19: Report of two Cases Babamahmoodi, Abdolreza Moniri, Afshin Sadr, Makan Poorhosseini, Seyed Mohammad Rezaei, Mitra Marjani, Majid Velayati, Ali Akbar Tanaffos Case Report COVID-19 leads to mild symptoms within the majority of infected patients, but can cause severe multiple organ failure and death. There is only limited information regarding the consequences of this new emerging infection with congenital disorders. According to the previous studies, many people with Down syndrome are considered high risk for complications related to respiratory diseases. We report two trisomy 21 patients who suffered from COVID-19 and summarize the early experience with COVID-19 and Down syndrome. The course of the disease was severe in these two cases, and our concern is close monitoring of the patients with Down syndrome for early signs of COVID-19. National Research Institute of Tuberculosis and Lung Disease 2020-12 /pmc/articles/PMC8088146/ /pubmed/33959180 Text en Copyright© 2020 National Research Institute of Tuberculosis and Lung Disease https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle Case Report
Babamahmoodi, Abdolreza
Moniri, Afshin
Sadr, Makan
Poorhosseini, Seyed Mohammad
Rezaei, Mitra
Marjani, Majid
Velayati, Ali Akbar
Trisomy 21 as a Risk Factor for Severe Illness in COVID-19: Report of two Cases
title Trisomy 21 as a Risk Factor for Severe Illness in COVID-19: Report of two Cases
title_full Trisomy 21 as a Risk Factor for Severe Illness in COVID-19: Report of two Cases
title_fullStr Trisomy 21 as a Risk Factor for Severe Illness in COVID-19: Report of two Cases
title_full_unstemmed Trisomy 21 as a Risk Factor for Severe Illness in COVID-19: Report of two Cases
title_short Trisomy 21 as a Risk Factor for Severe Illness in COVID-19: Report of two Cases
title_sort trisomy 21 as a risk factor for severe illness in covid-19: report of two cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088146/
https://www.ncbi.nlm.nih.gov/pubmed/33959180
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