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Mycetoma due to Nocardia Africana/Nova Treated Successfully with Cotrimoxazole and Moxifloxacin

Nocardia africana is a recently identified organism and has rarely been reported to cause mycetoma. Here we report the case of a 40-year-old woman who presented with discharging sinuses and nodules for the past 7 years along with few discrete axillary lymph nodes. Cultures and Maldi-TOF MS (Matrix-a...

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Autores principales: Bhandari, Molisha, Kathuria, Sushruta, Khunger, Niti, Sharma, Bhawna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088171/
https://www.ncbi.nlm.nih.gov/pubmed/33959529
http://dx.doi.org/10.4103/idoj.IDOJ_533_20
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author Bhandari, Molisha
Kathuria, Sushruta
Khunger, Niti
Sharma, Bhawna
author_facet Bhandari, Molisha
Kathuria, Sushruta
Khunger, Niti
Sharma, Bhawna
author_sort Bhandari, Molisha
collection PubMed
description Nocardia africana is a recently identified organism and has rarely been reported to cause mycetoma. Here we report the case of a 40-year-old woman who presented with discharging sinuses and nodules for the past 7 years along with few discrete axillary lymph nodes. Cultures and Maldi-TOF MS (Matrix-assisted laser desorption/ionization–time of flight mass spectrometry) method identified the causative organism as Nocardia africana/nova. The organism was acid-fast positive on modified Ziehl-Neelsen stain and Gram's stain revealed branched filamentous beaded gram-positive bacilli, while histopathology showed granulation tissue along with few ill-defined epithelioid cell granulomas, with giant cells. Based on the sensitivity report, the patient was started on tablet moxifloxacin and cotrimoxazole, and has shown considerable improvement at 2.5 months of follow-up.
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spelling pubmed-80881712021-05-05 Mycetoma due to Nocardia Africana/Nova Treated Successfully with Cotrimoxazole and Moxifloxacin Bhandari, Molisha Kathuria, Sushruta Khunger, Niti Sharma, Bhawna Indian Dermatol Online J Case Report Nocardia africana is a recently identified organism and has rarely been reported to cause mycetoma. Here we report the case of a 40-year-old woman who presented with discharging sinuses and nodules for the past 7 years along with few discrete axillary lymph nodes. Cultures and Maldi-TOF MS (Matrix-assisted laser desorption/ionization–time of flight mass spectrometry) method identified the causative organism as Nocardia africana/nova. The organism was acid-fast positive on modified Ziehl-Neelsen stain and Gram's stain revealed branched filamentous beaded gram-positive bacilli, while histopathology showed granulation tissue along with few ill-defined epithelioid cell granulomas, with giant cells. Based on the sensitivity report, the patient was started on tablet moxifloxacin and cotrimoxazole, and has shown considerable improvement at 2.5 months of follow-up. Wolters Kluwer - Medknow 2021-02-22 /pmc/articles/PMC8088171/ /pubmed/33959529 http://dx.doi.org/10.4103/idoj.IDOJ_533_20 Text en Copyright: © 2021 Indian Dermatology Online Journal https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Bhandari, Molisha
Kathuria, Sushruta
Khunger, Niti
Sharma, Bhawna
Mycetoma due to Nocardia Africana/Nova Treated Successfully with Cotrimoxazole and Moxifloxacin
title Mycetoma due to Nocardia Africana/Nova Treated Successfully with Cotrimoxazole and Moxifloxacin
title_full Mycetoma due to Nocardia Africana/Nova Treated Successfully with Cotrimoxazole and Moxifloxacin
title_fullStr Mycetoma due to Nocardia Africana/Nova Treated Successfully with Cotrimoxazole and Moxifloxacin
title_full_unstemmed Mycetoma due to Nocardia Africana/Nova Treated Successfully with Cotrimoxazole and Moxifloxacin
title_short Mycetoma due to Nocardia Africana/Nova Treated Successfully with Cotrimoxazole and Moxifloxacin
title_sort mycetoma due to nocardia africana/nova treated successfully with cotrimoxazole and moxifloxacin
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088171/
https://www.ncbi.nlm.nih.gov/pubmed/33959529
http://dx.doi.org/10.4103/idoj.IDOJ_533_20
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