Cargando…

IL-6 Promotes the Proliferation and Immunosuppressive Function of Myeloid-Derived Suppressor Cells via the MAPK Signaling Pathway in Bladder Cancer

Muscle-invasive bladder cancer (MIBC) is characterized by a highly complex immune environment, which is not well understood. Interleukin-6 (IL-6) is generated and secreted by multifarious types of cells, including tumor cells. This study was aimed at demonstrating that the levels of IL-6 and the num...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Zhong, Zheng, Xinyi, Zhu, Yiwen, Yao, Zhixian, Zhao, Weiguang, Zhu, Youjia, Sun, Feng, Mu, Xingyu, Wang, Yong, He, Wanqing, Liu, Zhihong, Wu, Ke, Zheng, Junhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088376/ https://www.ncbi.nlm.nih.gov/pubmed/33981768 http://dx.doi.org/10.1155/2021/5535578

Ejemplares similares

Comprehensive Characterization of Metabolism-Associated Subtypes of Renal Cell Carcinoma to Aid Clinical Therapy
por: Yao, Zhixian, et al.
Publicado: (2022)

Accumulation of CD45RO+CD8+ T cells is a diagnostic and prognostic biomarker for clear cell renal cell carcinoma
por: Wu, Ke, et al.
Publicado: (2021)

Long Noncoding RNA PVT1 Promotes Prostate Cancer Metastasis by Increasing NOP2 Expression via Targeting Tumor Suppressor MicroRNAs
por: Sun, Feng, et al.
Publicado: (2020)

Long noncoding RNA LINC00963 induces NOP2 expression by sponging tumor suppressor miR-542-3p to promote metastasis in prostate cancer
por: Sun, Feng, et al.
Publicado: (2020)

The ceRNA PVT1 inhibits proliferation of ccRCC cells by sponging miR-328-3p to elevate FAM193B expression
por: Xie, Guohai, et al.
Publicado: (2021)

The mTOR signal regulates myeloid-derived suppressor cells differentiation and immunosuppressive function in acute kidney injury
por: Zhang, Chao, et al.
Publicado: (2017)

Impaired immunosuppressive role of myeloid-derived suppressor cells in acquired aplastic anemia
por: Dong, Peiyuan, et al.
Publicado: (2022)

Immunosuppressive Effects of Myeloid-Derived Suppressor Cells in Cancer and Immunotherapy
por: Krishnamoorthy, Mithunah, et al.
Publicado: (2021)

Prognostic nomogram for bladder cancer with brain metastases: a National Cancer Database analysis
por: Yao, Zhixian, et al.
Publicado: (2019)

Targeting Myeloid-Derived Suppressor Cells to Bypass Tumor-Induced Immunosuppression
por: Fleming, Viktor, et al.
Publicado: (2018)

Myeloid Derived Suppressor Cells: Key Drivers of Immunosuppression in Ovarian Cancer
por: Baert, Thaïs, et al.
Publicado: (2019)

Physical activity delays accumulation of immunosuppressive myeloid-derived suppressor cells
por: Garritson, Jacob, et al.
Publicado: (2020)

Myeloid-derived suppressor cells as immunosuppressive regulators and therapeutic targets in cancer
por: Li, Kai, et al.
Publicado: (2021)

Construction and validation of a machine learning‐based nomogram: A tool to predict the risk of getting severe coronavirus disease 2019 (COVID‐19)
por: Yao, Zhixian, et al.
Publicado: (2021)

Targeting myeloid derived suppressor cells reverts immune suppression and sensitizes BRAF-mutant papillary thyroid cancer to MAPK inhibitors
por: Zhang, Peitao, et al.
Publicado: (2022)

Immunosuppressive Role of Myeloid-Derived Suppressor Cells and Therapeutic Targeting in Lung Cancer
por: Ma, Jie, et al.
Publicado: (2018)

Immunosuppression mediated by myeloid-derived suppressor cells (MDSCs) during tumour progression
por: Groth, Christopher, et al.
Publicado: (2018)

Glucosamine Interferes With Myelopoiesis and Enhances the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells
por: Lin, Eric Chang-Yi, et al.
Publicado: (2021)

Inhibition of fatty acid oxidation modulates immunosuppressive functions of myeloid-derived suppressor cells and enhances cancer therapies
por: Al-Khami, Amir A, et al.
Publicado: (2015)

Increased IL-17 production correlates with immunosuppression involving myeloid-derived suppressor cells and nutritional impairment in patients with various gastrointestinal cancers
por: YAZAWA, TAKASHI, et al.
Publicado: (2013)

The prediction for development of COVID-19 in global major epidemic areas through empirical trends in China by utilizing state transition matrix model
por: Zheng, Zhong, et al.
Publicado: (2020)

Long noncoding RNA Pvt1 regulates the immunosuppression activity of granulocytic myeloid-derived suppressor cells in tumor-bearing mice
por: Zheng, Yu, et al.
Publicado: (2019)

Author Correction: Targeting myeloid derived suppressor cells reverts immune suppression and sensitizes BRAF-mutant papillary thyroid cancer to MAPK inhibitors
por: Zhang, Peitao, et al.
Publicado: (2022)

Polysaccharide from Lentinus edodes Inhibits the Immunosuppressive Function of Myeloid-Derived Suppressor Cells
por: Wu, Hao, et al.
Publicado: (2012)

Lipid Metabolic Pathways Confer the Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Tumor
por: Yan, Dehong, et al.
Publicado: (2019)

RPN13/ADRM1 inhibitor reverses immunosuppression by myeloid-derived suppressor cells
por: Soong, Ruey-Shyang, et al.
Publicado: (2016)

Myeloid-Derived Suppressor Cells: Major Figures that Shape the Immunosuppressive and Angiogenic Network in Cancer
por: Vetsika, Eleni-Kyriaki, et al.
Publicado: (2019)

Myeloid-Derived Suppressor Cells Are Increased in Lung Transplant Recipients and Regulated by Immunosuppressive Therapy
por: Iglesias-Escudero, María, et al.
Publicado: (2022)

Myeloid-derived suppressor cells: key immunosuppressive regulators and therapeutic targets in hematological malignancies
por: Wang, Shifen, et al.
Publicado: (2023)

TGF-β Enhances Immunosuppression of Myeloid-Derived Suppressor Cells to Induce Transplant Immune Tolerance Through Affecting Arg-1 Expression
por: Cao, Peng, et al.
Publicado: (2022)

Myeloid-derived suppressor cells cross-talk with B10 cells by BAFF/BAFF-R pathway to promote immunosuppression in cervical cancer
por: Jianyi, Ding, et al.
Publicado: (2022)

Gut fungi enhances immunosuppressive function of myeloid-derived suppressor cells by activating PKM2-dependent glycolysis to promote colorectal tumorigenesis
por: Zhang, Zhiyong, et al.
Publicado: (2022)

Granulocytic Myeloid-Derived Suppressor Cell Exosomal Prostaglandin E2 Ameliorates Collagen-Induced Arthritis by Enhancing IL-10(+) B Cells
por: Wu, Xinyu, et al.
Publicado: (2020)

Immunosuppression by Inflammation-Stimulated Amplification of Myeloid-Derived Suppressor Cells and Changes in Expression of Immune Checkpoint HHLA2 in Chronic Obstructive Pulmonary Disease
por: Xu, Lijuan, et al.
Publicado: (2023)

Accumulation of myeloid-derived suppressor cells (MDSCs) induced by low levels of IL-6 correlates with poor prognosis in bladder cancer
por: Yang, Guoliang, et al.
Publicado: (2017)

Correction to: Myeloid-derived suppressor cells cross-talk with B10 cells by BAFF/BAFF-R pathway to promote immunosuppression in cervical cancer
por: Jianyi, Ding, et al.
Publicado: (2022)

Myeloid-Derived Suppressor Cells Interact with Tumors in Terms of Myelopoiesis, Tumorigenesis and Immunosuppression: Thick as Thieves
por: Sevko, Alexandra, et al.
Publicado: (2012)

Myeloid-derived suppressor cell and macrophage exert distinct angiogenic and immunosuppressive effects in breast cancer
por: Fang, Zhaoxu, et al.
Publicado: (2017)

Modulation of Immunosuppression by Oligonucleotide-Based Molecules and Small Molecules Targeting Myeloid-Derived Suppressor Cells
por: Lim, Jihyun, et al.
Publicado: (2020)

TRAF6 Regulates the Immunosuppressive Effects of Myeloid-Derived Suppressor Cells in Tumor-Bearing Host
por: Song, Ge, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_k6e8nbeps498i29hn9muhpamei