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Mesolimbic opioid-dopamine interaction is disrupted in obesity but recovered by weight loss following bariatric surgery
Obesity is a growing burden to health and the economy worldwide. Obesity is associated with central µ-opioid receptor (MOR) downregulation and disruption of the interaction between MOR and dopamine D(2) receptor (D(2)R) system in the ventral striatum. Weight loss recovers MOR function, but it remain...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088437/ https://www.ncbi.nlm.nih.gov/pubmed/33934103 http://dx.doi.org/10.1038/s41398-021-01370-2 |