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Identification of homozygous haplotypes carrying putative recessive lethal mutations that compromise fertility traits in French Lacaune dairy sheep

BACKGROUND: Homozygous recessive deleterious mutations can cause embryo/fetal or neonatal lethality, or genetic defects that affect female fertility and animal welfare. In livestock populations under selection, the frequency of such lethal mutations may increase due to inbreeding, genetic drift, and...

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Detalles Bibliográficos
Autores principales: Ben Braiek, Maxime, Fabre, Stéphane, Hozé, Chris, Astruc, Jean-Michel, Moreno-Romieux, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088666/
https://www.ncbi.nlm.nih.gov/pubmed/33932977
http://dx.doi.org/10.1186/s12711-021-00634-1