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Early return to continence and potency with use of dehydrated human umbilical cord graft at the time of robot‐assisted radical prostatectomy: A case study and analysis of relevant literature

INTRODUCTION: Robot‐assisted radical prostatectomy often causes damage to the neurovascular bundle which results in erectile dysfunction and urinary incontinence. Recovery may take months; however, dehydrated umbilical cord allografts appear to offer an advantage in terms of a faster return to conti...

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Autores principales: Krol, Bridget C, Hemal, Ashok K, Peak, Taylor, Liu, Shuo, Pathak, Ram A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088895/
https://www.ncbi.nlm.nih.gov/pubmed/33977245
http://dx.doi.org/10.1002/iju5.12267
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author Krol, Bridget C
Hemal, Ashok K
Peak, Taylor
Liu, Shuo
Pathak, Ram A
author_facet Krol, Bridget C
Hemal, Ashok K
Peak, Taylor
Liu, Shuo
Pathak, Ram A
author_sort Krol, Bridget C
collection PubMed
description INTRODUCTION: Robot‐assisted radical prostatectomy often causes damage to the neurovascular bundle which results in erectile dysfunction and urinary incontinence. Recovery may take months; however, dehydrated umbilical cord allografts appear to offer an advantage in terms of a faster return to continence and potency. CASE PRESENTATION: A 67‐year‐old male, who presented with intermediate‐risk prostate cancer, underwent a bilateral nerve‐sparing radical prostatectomy and placement of dehydrated human umbilical cord graft. Four weeks post‐prostatectomy, the patient reported minimal stress urinary incontinence and erections with 75% rigidity. Three months post‐prostatectomy, the patient noted improved continence and erections with 100% rigidity. CONCLUSION: To our knowledge, this is the second experience reported in the literature evaluating the use of umbilical cord allograft during robot‐assisted radical prostatectomy, with promising results, and it is the first reported case to analyze potency as an outcome.
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spelling pubmed-80888952021-05-10 Early return to continence and potency with use of dehydrated human umbilical cord graft at the time of robot‐assisted radical prostatectomy: A case study and analysis of relevant literature Krol, Bridget C Hemal, Ashok K Peak, Taylor Liu, Shuo Pathak, Ram A IJU Case Rep Case Reports INTRODUCTION: Robot‐assisted radical prostatectomy often causes damage to the neurovascular bundle which results in erectile dysfunction and urinary incontinence. Recovery may take months; however, dehydrated umbilical cord allografts appear to offer an advantage in terms of a faster return to continence and potency. CASE PRESENTATION: A 67‐year‐old male, who presented with intermediate‐risk prostate cancer, underwent a bilateral nerve‐sparing radical prostatectomy and placement of dehydrated human umbilical cord graft. Four weeks post‐prostatectomy, the patient reported minimal stress urinary incontinence and erections with 75% rigidity. Three months post‐prostatectomy, the patient noted improved continence and erections with 100% rigidity. CONCLUSION: To our knowledge, this is the second experience reported in the literature evaluating the use of umbilical cord allograft during robot‐assisted radical prostatectomy, with promising results, and it is the first reported case to analyze potency as an outcome. John Wiley and Sons Inc. 2021-02-17 /pmc/articles/PMC8088895/ /pubmed/33977245 http://dx.doi.org/10.1002/iju5.12267 Text en © 2021 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Urological Association https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Krol, Bridget C
Hemal, Ashok K
Peak, Taylor
Liu, Shuo
Pathak, Ram A
Early return to continence and potency with use of dehydrated human umbilical cord graft at the time of robot‐assisted radical prostatectomy: A case study and analysis of relevant literature
title Early return to continence and potency with use of dehydrated human umbilical cord graft at the time of robot‐assisted radical prostatectomy: A case study and analysis of relevant literature
title_full Early return to continence and potency with use of dehydrated human umbilical cord graft at the time of robot‐assisted radical prostatectomy: A case study and analysis of relevant literature
title_fullStr Early return to continence and potency with use of dehydrated human umbilical cord graft at the time of robot‐assisted radical prostatectomy: A case study and analysis of relevant literature
title_full_unstemmed Early return to continence and potency with use of dehydrated human umbilical cord graft at the time of robot‐assisted radical prostatectomy: A case study and analysis of relevant literature
title_short Early return to continence and potency with use of dehydrated human umbilical cord graft at the time of robot‐assisted radical prostatectomy: A case study and analysis of relevant literature
title_sort early return to continence and potency with use of dehydrated human umbilical cord graft at the time of robot‐assisted radical prostatectomy: a case study and analysis of relevant literature
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088895/
https://www.ncbi.nlm.nih.gov/pubmed/33977245
http://dx.doi.org/10.1002/iju5.12267
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