Ghent Older People’s Prescriptions Community Pharmacy Screening (GheOP(3)S)-Tool Version 2: Update of a Tool to Detect Drug-Related Problems in Older People in Primary Care

BACKGROUND: The Ghent Older People’s Prescriptions community Pharmacy Screening (GheOP(3)S)-tool was developed in 2016 as a screening tool to detect drug-related problems (DRPs) and to help in performing medication reviews in older people (≥ 65 years). OBJECTIVE: This study aimed to revise and update the GheOP(3)S-tool. METHODS: Users’ comments were collected to improve the usability and appropriateness of the original GheOP(3)S-tool, followed by a two-round modified Delphi process according to the RAND/UCLA appropriateness method. This included a literature review, a round zero meeting, a first written round (with 15 international and multidisciplinary experts) and a second face-to-face round (with 11 experts) to change, delete or add GheOP(3)S-criteria. An additional third round with 14 community pharmacists was organised to preserve criteria applicable in the current community pharmacy practice. RESULTS: The updated GheOP(3)S-tool consists of five lists of DRPs and a new addendum containing medications that should be avoided or used with caution in older people with reduced renal function. During the first two rounds, related criteria were grouped, 14 criteria were added and 17 criteria were deleted from the original tool. All criteria were deemed applicable in round 3. This led to a final tool (version 2) with 64 GheOP(3)S-criteria. CONCLUSION: GheOP(3)S-criteria were revised and updated according to experts’ agreement on their clinical relevance and recent scientific evidence. Future studies should investigate the impact of pharmacist-led medication reviews with GheOP(3)S-tool version 2 on clinical, humanistic and economic outcomes in primary care. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40266-021-00862-6.