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Transition of blood glucose level in a patient with pregnancy‐associated fulminant type 1 diabetes mellitus

We report on the transition in blood glucose levels before and after the onset of fulminant type 1 diabetes mellitus in a perinatal woman. In week 38 of pregnancy, before which the patient had normal glucose tolerance, idiopathic acute pancreatitis was diagnosed. Five days thereafter, she became hyp...

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Autores principales: Ichikawa, Takahiro, Kitae, Aya, Takeda, Sorou, Sueyoshi, Atsushi, Hamaguchi, Masahide, Fukui, Michiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089018/
https://www.ncbi.nlm.nih.gov/pubmed/33000569
http://dx.doi.org/10.1111/jdi.13419
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author Ichikawa, Takahiro
Kitae, Aya
Takeda, Sorou
Sueyoshi, Atsushi
Hamaguchi, Masahide
Fukui, Michiaki
author_facet Ichikawa, Takahiro
Kitae, Aya
Takeda, Sorou
Sueyoshi, Atsushi
Hamaguchi, Masahide
Fukui, Michiaki
author_sort Ichikawa, Takahiro
collection PubMed
description We report on the transition in blood glucose levels before and after the onset of fulminant type 1 diabetes mellitus in a perinatal woman. In week 38 of pregnancy, before which the patient had normal glucose tolerance, idiopathic acute pancreatitis was diagnosed. Five days thereafter, she became hypoglycemic, so we closely monitored her blood glucose levels. A total of 13 days later, she was hyperglycemic with a blood glucose level >16.0 mmol/L and glycated hemoglobin of 6.4%. Her fasting serum C‐peptide reactivity level was 3.6 ng/mL on the 5th day, and 0.2 ng/mL on the 18th day. Multiple insulin injection therapy was administered since the 18th day; after that, ketoacidosis did not occur. The patient was diagnosed with fulminant type 1 diabetes mellitus based on hyperglycemia without high glycated hemoglobin levels and sudden onset insulin‐dependent diabetes. Monitoring glucose levels in the case of idiopathic acute pancreatitis during pregnancy and prompt initiation of insulin therapy are important.
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spelling pubmed-80890182021-05-10 Transition of blood glucose level in a patient with pregnancy‐associated fulminant type 1 diabetes mellitus Ichikawa, Takahiro Kitae, Aya Takeda, Sorou Sueyoshi, Atsushi Hamaguchi, Masahide Fukui, Michiaki J Diabetes Investig Articles We report on the transition in blood glucose levels before and after the onset of fulminant type 1 diabetes mellitus in a perinatal woman. In week 38 of pregnancy, before which the patient had normal glucose tolerance, idiopathic acute pancreatitis was diagnosed. Five days thereafter, she became hypoglycemic, so we closely monitored her blood glucose levels. A total of 13 days later, she was hyperglycemic with a blood glucose level >16.0 mmol/L and glycated hemoglobin of 6.4%. Her fasting serum C‐peptide reactivity level was 3.6 ng/mL on the 5th day, and 0.2 ng/mL on the 18th day. Multiple insulin injection therapy was administered since the 18th day; after that, ketoacidosis did not occur. The patient was diagnosed with fulminant type 1 diabetes mellitus based on hyperglycemia without high glycated hemoglobin levels and sudden onset insulin‐dependent diabetes. Monitoring glucose levels in the case of idiopathic acute pancreatitis during pregnancy and prompt initiation of insulin therapy are important. John Wiley and Sons Inc. 2020-10-26 2021-05 /pmc/articles/PMC8089018/ /pubmed/33000569 http://dx.doi.org/10.1111/jdi.13419 Text en © 2020 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Articles
Ichikawa, Takahiro
Kitae, Aya
Takeda, Sorou
Sueyoshi, Atsushi
Hamaguchi, Masahide
Fukui, Michiaki
Transition of blood glucose level in a patient with pregnancy‐associated fulminant type 1 diabetes mellitus
title Transition of blood glucose level in a patient with pregnancy‐associated fulminant type 1 diabetes mellitus
title_full Transition of blood glucose level in a patient with pregnancy‐associated fulminant type 1 diabetes mellitus
title_fullStr Transition of blood glucose level in a patient with pregnancy‐associated fulminant type 1 diabetes mellitus
title_full_unstemmed Transition of blood glucose level in a patient with pregnancy‐associated fulminant type 1 diabetes mellitus
title_short Transition of blood glucose level in a patient with pregnancy‐associated fulminant type 1 diabetes mellitus
title_sort transition of blood glucose level in a patient with pregnancy‐associated fulminant type 1 diabetes mellitus
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089018/
https://www.ncbi.nlm.nih.gov/pubmed/33000569
http://dx.doi.org/10.1111/jdi.13419
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