Cargando…

MYC/NBS1-Mediated DNA Damage Response is Involved in the Inhibitory Effect of Hydroxysafflor Yellow A on Glioma Cells

BACKGROUND: The role of Hydroxysafflor Yellow A (HSYA) in glioma is less studied, this research determined the effect of HSYA on glioma cells. METHODS: The expressions of MYC and NBS1 in glioma tissues were detected by bioinformatics analysis and verified by RT-qPCR. The target relationship between...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Dongfang, Huang, Tao, Tian, Qilong, Wang, Julei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089107/ https://www.ncbi.nlm.nih.gov/pubmed/33953544 http://dx.doi.org/10.2147/DDDT.S288841

Ejemplares similares

Therapeutic Potential of Hydroxysafflor Yellow A on Cardio-Cerebrovascular Diseases
por: Bai, Xue, et al.
Publicado: (2020)

Establishment of Fluorescence Sensitization Method for Hydroxysafflor Yellow A
por: Haiyan, CAO, et al.
Publicado: (2020)

Nanoemulsions of Hydroxysafflor Yellow A for Enhancing Physicochemical and In Vivo Performance
por: Zhang, Yingjie, et al.
Publicado: (2023)

Hydroxysafflor yellow A protects against angiotensin II-induced hypertrophy
por: Ni, Bin, et al.
Publicado: (2018)

Superior Stability of Hydroxysafflor Yellow A in Xuebijing Injection and the Associated Mechanism
por: Pu, Weiling, et al.
Publicado: (2017)

Mechanism of hydroxysafflor yellow A on acute liver injury based on transcriptomics
por: Hou, Xiangmei, et al.
Publicado: (2022)

Hydroxysafflor Yellow A Attenuates Hydrogen Peroxide-Induced Oxidative Damage on Human Umbilical Vein Endothelial Cells
por: Xie, Yuefeng, et al.
Publicado: (2020)

Hydroxysafflor Yellow A Attenuates Lipopolysaccharide-Induced Neurotoxicity and Neuroinflammation in Primary Mesencephalic Cultures
por: Wang, Tian, et al.
Publicado: (2018)

Hydroxysafflor yellow A improved retinopathy via Nrf2/HO-1 pathway in rats
por: Sun, Zhihui, et al.
Publicado: (2022)

NBS1 and multiple regulations of DNA damage response
por: Komatsu, Kenshi
Publicado: (2016)

Synergistic neuroprotective effects of Danshensu and hydroxysafflor yellow A on cerebral ischemia-reperfusion injury in rats
por: Xu, Hang, et al.
Publicado: (2017)

Metabolomics reveals the effects of hydroxysafflor yellow A on neurogenesis and axon regeneration after experimental traumatic brain injury
por: Hu, En, et al.
Publicado: (2023)

Hydroxysafflor Yellow A protects spinal cords from ischemia/reperfusion injury in rabbits
por: Shan, Le-qun, et al.
Publicado: (2010)

Hydroxysafflor Yellow A Protects Neurons From Excitotoxic Death through Inhibition of NMDARs
por: Wang, Xingtao, et al.
Publicado: (2016)

Hydroxysafflor yellow A attenuates the expression of inflammatory cytokines in acute soft tissue injury
por: Dong, Fang, et al.
Publicado: (2017)

Hydroxysafflor Yellow A: A Promising Therapeutic Agent for a Broad Spectrum of Diseases
por: Ao, Hui, et al.
Publicado: (2018)

Hydroxysafflor Yellow A Shows Protection against PPARγ Inactivation in Nitrosative Neurons
por: Sun, Li, et al.
Publicado: (2018)

Hydroxysafflor yellow A improves established monocrotaline-induced pulmonary arterial hypertension in rats
por: Han, Xiaotong, et al.
Publicado: (2016)

Protective effect of hydroxysafflor yellow A on MSCs against senescence induced by d-galactose
por: Song, Xiaoqing, et al.
Publicado: (2022)

Integrated metabolomics and network pharmacology to reveal the mechanisms of hydroxysafflor yellow A against acute traumatic brain injury
por: Li, Teng, et al.
Publicado: (2021)

Oral Bioavailability-Enhancing and Anti-obesity Effects of Hydroxysafflor Yellow A in Natural Deep Eutectic Solvent
por: Gao, Huan, et al.
Publicado: (2022)

Enhanced effect and mechanism of water-in-oil microemulsion as an oral delivery system of hydroxysafflor yellow A
por: Qi, Jianping, et al.
Publicado: (2011)

Hydroxysafflor yellow A exerts antioxidant effects in a rat model of traumatic brain injury
por: Wang, Yang, et al.
Publicado: (2016)

Hydroxysafflor Yellow A Ameliorates Myocardial Ischemia/Reperfusion Injury by Suppressing Calcium Overload and Apoptosis
por: Ye, Jingxue, et al.
Publicado: (2021)

Hydroxysafflor Yellow A Promoted Bone Mineralization and Inhibited Bone Resorption Which Reversed Glucocorticoids-Induced Osteoporosis
por: Liu, Li, et al.
Publicado: (2018)

Hydroxysafflor Yellow A Exerts Anti-Inflammatory Effects Mediated by SIRT1 in Lipopolysaccharide-Induced Microglia Activation
por: Qin, Xiude, et al.
Publicado: (2020)

Protective potential of hydroxysafflor yellow A in cerebral ischemia and reperfusion injury: An overview of evidence from experimental studies
por: Yu, Lu, et al.
Publicado: (2022)

Comparative Analysis of the Effects of Hydroxysafflor Yellow A and Anhydrosafflor Yellow B in Safflower Series of Herb Pairs Using Prep-HPLC and a Selective Knock-Out Approach
por: Qu, Cheng, et al.
Publicado: (2016)

Proteomic investigation of effects of hydroxysafflor yellow A in oxidized low-density lipoprotein-induced endothelial injury
por: Ye, Feng, et al.
Publicado: (2017)

Co-delivery of deferoxamine and hydroxysafflor yellow A to accelerate diabetic wound healing via enhanced angiogenesis
por: Gao, Si-Qian, et al.
Publicado: (2018)

Pharmacological Actions, Molecular Mechanisms, Pharmacokinetic Progressions, and Clinical Applications of Hydroxysafflor Yellow A in Antidiabetic Research
por: Zhang, Xilan, et al.
Publicado: (2021)

Protective effect of hydroxysafflor yellow A on cyclosporin A-induced renal oxidative stress in vitro and in vivo
por: Wang, Jiyuan, et al.
Publicado: (2022)

Hydroxysafflor Yellow A Phytosomes Administered via Intervaginal Space Injection Ameliorate Pulmonary Fibrosis in Mice
por: Li, Tingting, et al.
Publicado: (2022)

Protective effect of hydroxysafflor yellow A on renal ischemia‑reperfusion injury by targeting the Akt‑Nrf2 axis in mice
por: Wang, Yueming, et al.
Publicado: (2022)

Paeoniflorin and Hydroxysafflor Yellow A in Xuebijing Injection Attenuate Sepsis-Induced Cardiac Dysfunction and Inhibit Proinflammatory Cytokine Production
por: Wang, Xin-Tong, et al.
Publicado: (2021)

Functional Role of NBS1 in Radiation Damage Response and Translesion DNA Synthesis
por: Saito, Yuichiro, et al.
Publicado: (2015)

Hydroxysafflor Yellow A Blocks HIF-1α Induction of NOX2 and Protects ZO-1 Protein in Cerebral Microvascular Endothelium
por: Li, Yi, et al.
Publicado: (2022)

Hydroxysafflor Yellow A Ameliorates Renal Fibrosis by Suppressing TGF-β1-Induced Epithelial-to-Mesenchymal Transition
por: Hu, Naping, et al.
Publicado: (2016)

Hydroxysafflor yellow A alleviates myocardial ischemia/reperfusion in hyperlipidemic animals through the suppression of TLR4 signaling
por: Han, Dan, et al.
Publicado: (2016)

Hydroxysafflor Yellow A Suppresses Platelet Activating Factor-Induced Activation of Human Small Airway Epithelial Cells
por: Guo, Xinjing, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pfs95kdkj648hisdrt80va5o6o