Severe Disease Activity and Liver Fibrosis Are Associated With a Lack of Hepatic Mitochondrial Adaptation in Patients With NASH

Dysfunctional mitochondrial function is believed to play a vital role in the progression of nonalcoholic steatohepatitis (NASH) to advanced fibrosis and cirrhosis. However, most evidence arises from animal models while there is limited data in humans. The characteristic histological finding of NASH...

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Detalles Bibliográficos
Autores principales: Kalavalapalli, Srilaxmi, Barb, Diana, Leiva, Eddison Godinez, Lomonaco, Romina M, Fanous, Nada, Chug, Radhika, Friedman, Jeffrey, Rabe, Matthew, Cowan, Tyler M, Dillard, Rachel, Poulton, Danielle, Mansour, Lydia, Shrestha, Sulav, Cusi, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Adipose Tissue, Appetite, and Obesity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089219/
http://dx.doi.org/10.1210/jendso/bvab048.053

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