Blocking Oxidized Phospholipids Attenuates the Age-Associated, but Not the Ovariectomy- or Unloading- Induced, Bone Loss in Mice

Oxidized phospholipids (OxPL), such as oxidized phosphatidylcholine, are generated by oxidative stress (OS)-induced lipid peroxidation. E06 IgM is a natural antibody that recognizes the phosphocholine (PC) moiety of OxPLs, but not native PLs. Generation of transgenic mice expressing a single chain (...

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Detalles Bibliográficos
Autores principales: Palmieri, Michela, Joseph, Teenamol E, Warren, Aaron, Gomez-acevedo, Horacio, Xiong, Jinhu, Witztum, Joseph Lee, Manolagas, Stavros C, Ambrogini, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Bone and Mineral Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089297/
http://dx.doi.org/10.1210/jendso/bvab048.470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089297/
http://dx.doi.org/10.1210/jendso/bvab048.470

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