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Identification of a Novel DICER1 Germline Mutation in Thyroid Follicular Adenoma Using Whole Exome Sequencing
Backgrounds: DICER1 protein is a member of the ribonuclease III family of proteins that cleaves non-coding small RNA precursors to generate mature miRNAs, which in turn regulate gene expression post-transcriptionally. Thyroid abnormalities are frequently observed in DICER1 syndrome with multinodular...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089489/ http://dx.doi.org/10.1210/jendso/bvab048.1819 |