Cargando…

PTH Protects Osteocytes From Oxidative Stress and Cellular Senescence

Age-induced osteoporosis is characterized by a progressive decline in bone formation and increase in bone resorption with uncoupled activities of osteoblasts and osteoclasts. Parathyroid hormone (PTH) is used in the clinic to treat osteoporosis due to its anabolic actions on bone via binding to the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Uda, Yuhei, Santos, Roberto, Kochen, Alejandro, Newell, Carly, Huang, Tim Y, Pajevic, Paola Divieti
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Bone and Mineral Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089505/ http://dx.doi.org/10.1210/jendso/bvab048.485

Ejemplares similares

MON-LB087 Synthesis of Osteocyte-Derived Phosphaturic Hormone FGF23 via IP3/PKC Signaling Downstream of the Extra-Large Gα Subunit (XLαs)
por: He, Qing, et al.
Publicado: (2019)

SAT-402 Investigating Analogues of Parathyroid Hormone (PTH) and PTH-Related Peptide (PTHrP) to Improve Anabolic: Catabolic Response Ratios Using UMR106-01 Osteocytic Cells
por: Oladapo, Oladipo Posi, et al.
Publicado: (2020)

OR07-01 Identification of the First Case of Acquired Autoimmune Parathyroid Hormone (PTH) Resistance Due to PTH1 Receptor (PTH1R) Autoantibodies
por: Mandl, Adel, et al.
Publicado: (2020)

SAT-396 A Non-Surgical Animal Model of Hypoparathyroidism for Testing PTH Analogues
por: Ramezani-Pour, Narjes, et al.
Publicado: (2020)

Improving the Accuracy and Reliability of Parathyroid Hormone Levels Through the Mass-Spectrometric Measurement of Full-length PTH and C-Terminal PTH Fragments
por: Ulmer, Candice Z, et al.
Publicado: (2021)

SAT-LB72 Design of the PaTH Forward Phase 2 Trial of TransCon PTH, a Long-Acting PTH, in Patients With Hypoparathyroidism
por: Khan, Aliya Aziz, et al.
Publicado: (2020)

MON-538 Ca(2+)Allostery in PTH-Receptor Signaling
por: White, Alex, et al.
Publicado: (2019)

Ectopic Intact PTH Secretion Causing Humoral Hypercalcemia of Malignancy
por: Rauf, Mohammad Talha, et al.
Publicado: (2021)

PSAT158 Dimeric [Cys25]PTH(1-34) and Monomeric PTH(1-34) Differentially Regulate the Expression of Genes Related to Calcium Homeostasis in Bone and Kidney
por: Lee, Sihoon, et al.
Publicado: (2022)

OR30-3 Structural Basis of Activation and Sustained Signaling by the PTH Receptor
por: Sutkeviciute, Ieva, et al.
Publicado: (2019)

MON-343 The Mystery of Recurrent PTH-Independent Hypercalcemia with Severe Hypophosphatemia
por: Shaikh, Bilal, et al.
Publicado: (2020)

A Curious Case of PTH Independent Hypercalcemia Secondary to Silicone Injections
por: Matos, Moises, et al.
Publicado: (2021)

MON-533 Irisin in Post-Menopausal Women with Primary Hyperparathyroidism: An Interplay between Irisin and Pth
por: Palermo, Andrea, et al.
Publicado: (2019)

Rare Case of Severe Hypocalcemia Due to PTH Resistance Related to Diet Pill
por: Katkar, Rujuta Baban, et al.
Publicado: (2021)

SAT211 PTH-secreting Endometrial Carcinoma: A Rare Cause of Hypercalcemia
por: Fanous, Ereeny, et al.
Publicado: (2023)

MON-534 Reduced PTH Levels in Adolescents with Anorexia Nervosa: Implication for Kidney and Bone
por: Lenherr-Taube, Nina, et al.
Publicado: (2019)

SAT-503 A Rare Case of Hypercalcemia Due to PTH Secreting Lung Adenocarcinoma
por: Gonzalez-Falero, Andrea, et al.
Publicado: (2019)

SAT-388 Dry Cough as Only Sign of a Parathyroid Adenoma Producer of PTH
por: Selman-Geara, Antonio, et al.
Publicado: (2020)

Treatment-Resistant Hypercalcemia Secondary to Ectopic PTH Hypersecretion From Disseminated Ovarian Cancer
por: Balinski, Alexander M, et al.
Publicado: (2021)

SAT195 A Curious Case Of Severe Reversible PTH-mediated Hypercalcemia Of Pregnancy
por: Albanese, Isabella, et al.
Publicado: (2023)

THU474 Primary Hyperaldosteronism As A Cause Of PTH Elevation After Parathyroid Surgery
por: Thi, Wai Phyo, et al.
Publicado: (2023)

OR03-2 Different Effects of Abaloparatide and h-PTH(1-34) on Osteoclastogenesis and Bone Resorption
por: Arlt, Heike, et al.
Publicado: (2019)

SAT-492 Intact PTH Secretion from Hepatocellular Carcinoma in a Patient Presenting with Hypercalcemia
por: Weaver, Anne, et al.
Publicado: (2019)

OR07-03 Continuous Subcutaneous Delivery of RhPTH(1-84) by Pump in Adults with Hypoparathyroidism
por: Bove-Fenderson, Erin, et al.
Publicado: (2020)

Parathyroid hormone signaling in mature osteoblasts/osteocytes protects mice from age-related bone loss
por: Uda, Yuhei, et al.
Publicado: (2021)

SAT-494 A Very Rare Case: Hypercalcemia Caused by Ectopic PTH Secretion in Endometrial Cancer
por: Batarseh, Nour, et al.
Publicado: (2019)

Novel Method in Performing PTH Washout for Localizing Parathyroid Adenoma: Case Report & an Institute Experience in Qatar
por: Mohammad Salameh, Obada Khalil, et al.
Publicado: (2021)

OR23-01 The Nonredundant Role Of Beta-Amyloid In Mediating Tonic PTH Secretion In Physiological And Pathological States
por: Tu, Chia-Ling, et al.
Publicado: (2023)

MON-535 Relationship between Vitamin D and PTH: The Effect of Obesity and Weight Loss after Bariatric Surgery
por: Salazar, Daniela, et al.
Publicado: (2019)

SAT194 A Rare Case Of Untreated Primary Hyperparathyroidism With Extremely High PTH And Lytic Bone Lesions
por: Shah, Mauli, et al.
Publicado: (2023)

THU407 CRISPR/Cas9-based Knockout Of CFTR Alters Mechano-sensitivity And Proteomic Profile In An Osteocyte Model
por: Du, Wanting, et al.
Publicado: (2023)

SAT-408 Bioactivity of Long Acting PTH Fusion Molecules Tested in a Novel Non-Surgical Animal Model of Hypoparathyroidism
por: Wilkinson, Ian R, et al.
Publicado: (2020)

OR21-4 Comparison of the Effects of PTH (1-34), PTHrP (1-36) and Abaloparatide (ABL) on the Murine Osteoblast Transcriptome
por: He, Zhiming, et al.
Publicado: (2022)

OR21-1 The PaTH Forward Trial: Efficacy and Safety of TransCon PTH Through Week 84 for Adults With Hypoparathyroidism
por: Ahmed, Intekhab, et al.
Publicado: (2022)

SAT257 Efficacy Of Oral Cinacalcet In Non-PTH Non-Malignant Hypercalcemia From Excess 1,25 Dihydroxyvitamin D
por: Mohan, Sneha, et al.
Publicado: (2023)

SAT-386 Inconsistent Bilateral Arm Serum PTH Testing in Recurrent Hyperparathyroidism in a Patient Status-Post Parathyroid Auto-Transplantation
por: Jenkins, Craig, et al.
Publicado: (2020)

Serum Calcium Levels in Adult Patients With Chronic Hypoparathyroidism Treated With rhPTH(1–84) Compared With a Historical Control Cohort
por: Rejnmark, Lars, et al.
Publicado: (2021)

OR21-3 Spatial Signaling Bias of a Gain-of-Function PTH1R Mutant Associated with Delayed Ossification in Eiken Syndrome
por: Dean, Thomas, et al.
Publicado: (2022)

ODP118 PTH (1-34) Replacement Therapy for Hypoparathyroidism due to Sporadic Calcium Sensing Receptor Gain-of-Function Point Mutation
por: Basina, Marina, et al.
Publicado: (2022)

Risk of Chronic Kidney Disease in Adult Patients With Chronic Hypoparathyroidism Treated With rhPTH(1–84) Compared With a Historical Control Cohort
por: Gosmanova, Elvira, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1oud4jb50fqo7khlag4beisii6