Selective Somatostatin 5 (SST5) and Somatostatin 2 (SST2) Nonpeptide Agonists Potently Suppress Glucose- and Tolbutamide-Stimulated Dynamic Insulin Secretion From Isolated Human Islets

Congenital hyperinsulinism (HI) is the most common cause of persistent hypoglycemia in newborns and infants and arises from dysregulated insulin secretion. Rapid recognition and treatment are vital to prevent seizures, permanent developmental delays, coma, or even death. Very few medical options exi...

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Detalles Bibliográficos
Autores principales: Rico, Elizabeth, Zhao, Jian, Chen, Mi, Kusnetzow, Ana Karin, Zhu, Yun Fei, Betz, Stephen F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Diabetes Mellitus and Glucose Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089509/
http://dx.doi.org/10.1210/jendso/bvab048.663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089509/
http://dx.doi.org/10.1210/jendso/bvab048.663

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