iPSC-Derived Human Hepatocytes as a Novel Model to Investigate Thyroid Hormone Action and Signaling

Thyroid hormone (TH) actions are essential to normal metabolism and neurologic function. Abnormal TH levels can lead to significant morbidity including metabolic abnormalities, cardiac disease, and obesity. TH action is mediated by the thyroid hormone receptor (TR) isoforms and their coregulators. I...

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Detalles Bibliográficos
Autores principales: De Oliveira, Lorraine Soares, Lee, Nora, Kaserman, Joseph, Vella, Kristen R, Wilson, Andrew, Hollenberg, Anthony Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Thyroid
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089531/
http://dx.doi.org/10.1210/jendso/bvab048.1994

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