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Efficient Restoration of Beta Cell Dedifferentiation by Calorie Restriction With High Fat/Low Carbohydrate Diet in Obese Diabetes Model and the Possible Role of GLP-1

In type 2 diabetes, pancreatic beta cells are gradually ‘exhausted’ and fall into beta cell dysfunction, which proceeds more severe insulin dependence. Among the proposed mechanisms of beta cell dysfunction such as endoplasmic reticulum stress and oxidative stress, the beta cell heterogeneity has at...

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Detalles Bibliográficos
Autores principales:	Ishida, Emi, Lei, Xiao, Horiguchi, Kazuhiko, Matsumoto, Shunichi, Yoshino, Satoshi, Nakajima, Yasuyo, Yamada, Eijiro, Yamada, Masanobu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Diabetes Mellitus and Glucose Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089540/ http://dx.doi.org/10.1210/jendso/bvab048.896

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