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Is Metformin Use Associated With Decreased Thyroid Cancer Risk in Patients With Acromegaly?

Context: Acromegaly has long been blamed to portend an increased risk for benign and malignant thyroid neoplasia. Growth hormone (GH) and consequent insulin-like growth factor 1 (IGF-1) hypersecretion are implicated in cancer promotion. Metformin, a biguanide derived from the French lilac, is gainin...

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Detalles Bibliográficos
Autores principales: Kadioglu, Pinar, Sulu, Cem, Tay, Kubilay, Guzel, Suleyman, Sahin, Serdar, Durcan, Emre, Ozkaya, Hande Mefkure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089607/
http://dx.doi.org/10.1210/jendso/bvab048.1763