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Enhanced Insulin Signaling Through Its Receptor Is Needed for the Development of Hyperuricemia in Humans

Background: There is an association between insulin resistance (IR) and hyperuricemia but the direction of causalityand mechanisms are unclear. In obesity and lipodystrophy, IR is “selective”, with lack of insulin signalingcausing hyperglycemia, but enhanced insulin signaling causing dyslipidemia an...

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Detalles Bibliográficos
Autores principales: Haykal, Rasha, Kinzer, Alexandra, Abel, Brent, Startzell, Megan S, Cochran, Elaine, Brown, Rebecca J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089614/
http://dx.doi.org/10.1210/jendso/bvab048.839

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