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LGR4 and Its Extracellular Domain as Novel Regulators of ß-Cell Survival and Proliferation

Our lab has shown that RANK (Receptor activator of the NF-κB) by interacting with its ligand, RANKL, inhibits ß-cell proliferation and survival; which can be reversed by Osteoprotegerin (OPG). Recently, the G protein-coupled receptor LGR4 (leucine-rich repeat-containing G protein-coupled receptor 4)...

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Detalles Bibliográficos
Autores principales:	Filipowska, Joanna K, Kondegowda, Nagesha G, Vasavada, Rupangi C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Diabetes Mellitus and Glucose Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089736/ http://dx.doi.org/10.1210/jendso/bvab048.656

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