Cargando…

One Hormone for Two Receptors: Exploring Glucocorticoid Actions Mediated by the Glucocorticoid and Mineralocorticoid Receptors

Glucocorticoids are indispensable for mediating the response to stress, energy demands, development, and limiting inflammation. Once in the cell, these hormones exert their actions by activating nuclear receptors, transcription factors that regulate gene expression. The glucocorticoid receptor (GR)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Petrillo, Maria G, Jewell, Christine, Bortner, Carl D, Oakley, Robert H, Cidlowski, John A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Steroid Hormones and Receptors
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089835/ http://dx.doi.org/10.1210/jendso/bvab048.1655

Ejemplares similares

OR12-02 When the Glucocorticoid Receptor Meets the Mineralocorticoid Receptor in the Nucleus of Human Cells
por: Petrillo, Maria G, et al.
Publicado: (2020)

SAT-008 Overcoming BCL-2 Resistance in Glucocorticoid-Treated Tumor Lymphoid Cells
por: Bortner, Carl, et al.
Publicado: (2019)

Glucocorticoid Mediated Transcriptional Activity in Human Corneal Epithelial Cells Lacking the Glucocorticoid Receptor
por: Jonsson, Andrea Joyce, et al.
Publicado: (2021)

SAT-740 Plasma Glucocorticoids and Mineralocorticoids Are Associated to Metabolic Syndrome Features in Women
por: Ostinelli, Giada, et al.
Publicado: (2020)

The Impact of a Single Phosphorylation Site Mutation in the Glucocorticoid Receptor on the Molecular and Cellular Development of the Cerebral Cortex
por: Gupta, Herschel Raj, et al.
Publicado: (2021)

OR12-03 Mineralocorticoid and Glucocorticoid Receptors Adopt Distinct Quaternary Structures and Can Form Heteromultimers That Affect Chromatin-Binding Profiles
por: de la Rosa, Diego Alvarez, et al.
Publicado: (2020)

SUN-737 Induction of the Pro-Diabetic Gene DPP4 by Glucocorticoids: New Evidence of Pro-Inflammatory Effects in Macrophages
por: Diaz-Jimenez, David, et al.
Publicado: (2020)

SUN-008 The Glucocorticoid Receptor Is Essential For TGFβ and p38 MAPK Mediated Cancer Phenotypes in Triple Negative Breast Cancer
por: Perez Kerkvliet, Carlos, et al.
Publicado: (2019)

Glucocorticoid Receptor Condensates Link DNA-Dependent Receptor Dimerization and Transcriptional Transactivation
por: Frank, Filipp, et al.
Publicado: (2021)

SUN-019 The Selective Progesterone Receptor Modulator Ulipristal Acetate Blocks Glucocorticoid Receptor Transactivation
por: Smalls, Benjamin, et al.
Publicado: (2019)

The Effect of a Novel Glucocorticoid Receptor Antagonist (CORT113176) on Glucocorticoid and Insulin Receptor Sensitive Hepatic Gene (mRNA) Expression in a Neonatal Rat Model of Human Prematurity
por: Gehrand, Ashley, et al.
Publicado: (2021)

FRI164 The Glucocorticoid Receptor is Required for Efficient Aldosterone-induced Transcription by the Mineralocorticoid Receptor
por: Johnson, Thomas A, et al.
Publicado: (2023)

OR26-6 Glucocorticoid Receptor Quaternary Structure Drives Chromatin Occupancy and Transcriptional Outcome
por: Paakinaho, Ville, et al.
Publicado: (2019)

ODP651 Abnormal Primary Ciliogenesis in the Developing Mouse Kidney of Glucocorticoid Receptor-Deficient Mice
por: Cole, Timothy, et al.
Publicado: (2022)

OR07-4 Regulation of Mineralocorticoid Receptor Transactivation By Circadian Protein Timeless
por: Young, Morag
Publicado: (2022)

OR07-5 PARP1 Contributes to the Glucocorticoid Receptor Transcriptional Response And Influences the Skeletal Muscle Phenotype
por: Boocock, David, et al.
Publicado: (2022)

SUN-LB136 A Comparison of Androgen Receptor Splice Variant, AR-V7, and Glucocorticoid Receptor Activity in Prostate Cancer
por: Dash, Amit K, et al.
Publicado: (2020)

SUN-739 Next Generation AR Antagonists Increase Systemic Active Glucocorticoid Exposure by Altering Glucocorticoid Metabolism
por: Alyamani, Mohammad, et al.
Publicado: (2020)

OR26-4 Glucocorticoid Receptor Expression and Signaling During Critical Illness, in Relation to the Duration of Illness and the Systemic Glucocorticoid Availability: A Prospective, Observational, Cross-Sectional Human and a Translational Mouse Study
por: Téblick, Arno, et al.
Publicado: (2022)

Time of Day Regulates Renal Mineralocorticoid Receptor Transcriptional Control of Electrolyte Balance
por: Kanki, Monica, et al.
Publicado: (2021)

SAT-020 Empiric Determination of Daily Glucocorticoid Replacement Doses in Adrenal Insufficiency
por: Caetano, Celina, et al.
Publicado: (2019)

OR26-2 mTOR Interacts with the Mineralocorticoid Receptor to Regulate its Activation by Ligand
por: Gomez-Sanchez, Celso E, et al.
Publicado: (2022)

Carbonyl Reductase 1 Overexpression in Adipose Amplifies Local Glucocorticoid Action and Impairs Glucose Tolerance in Lean Mice
por: Bell, Rachel, et al.
Publicado: (2021)

OR26-3 USP19 Deubiquitinating Enzyme Functions as a Novel Co-Chaperone of Hsp90 to Regulate Glucocorticoid Receptor Levels
por: Bedard, Nathalie, et al.
Publicado: (2022)

Disruption of Adipose Tissue Metabolism by Glucocorticoids Is Attenuated With LXRβ Antagonism
por: Li, Jia Xu, et al.
Publicado: (2021)

ODP441 NErbB-2 and Androgen Receptor Regulate a Gene Signature Involved in Immune Response and Favorable Outcome in TNBC
por: Elizalde, Patricia, et al.
Publicado: (2022)

OR22-04 The Oncogenic Action Of Glucocorticoid Receptor In Prostate Cancer
por: Paakinaho, Ville
Publicado: (2023)

ODP444 The Effect of Glucocorticoid Therapy on Cardio-Metabolic Risk in Patients with Multiple Sclerosis
por: Brovkina, Snezhana, et al.
Publicado: (2022)

SAT-LB136 A Proteomic Approach to Identify Circulating Glucocorticoid Responsive Proteins in Humans
por: Inder, Warrick John, et al.
Publicado: (2020)

RF15 | PMON294 Disrupting a Key H-bond Network Drives Glucocorticoid Receptor Gene Suppression Without Off-target Gene Activation for Duchenne Muscular Dystrophy Treatment
por: Liu, Xu, et al.
Publicado: (2022)

Androgen Receptor Highjacks ErbB-2 Nuclear Function to Induce Triple Negative Breast Cancer Growth
por: Deamicis, Agustina Roldán, et al.
Publicado: (2021)

SAT-005 Gene Expression and Behavioral Alterations in Mice with Conditional Knockout of GR, MR, or Both GR and MR in the Hippocampus
por: Oakley, Robert, et al.
Publicado: (2019)

SAT-003 Therapeutic Glucocorticoids Prevent Local and Systemic Bone Loss but Exacerbate Muscle Wasting When Administered in Chronic Inflammation
por: Fenton, Chloe, et al.
Publicado: (2019)

OR09-3 11β-HSD1 Mediates a Partial Suppression of Muscle Atrophy in Chronic Inflammatory Disease in Response to Therapeutic Glucocorticoids
por: Webster, Justine, et al.
Publicado: (2019)

Mechanism of Action of Irilone as a Potentiator of Progesterone Receptor Signaling
por: Austin, Julia R, et al.
Publicado: (2021)

Quantifying the Protein Levels of All Nuclear Hormone Receptors by Mass Spectrometry
por: Saikali, Michael Fadi, et al.
Publicado: (2021)

SUN-015 Glucocorticoid Induction And Direct Genomic Regulation Of The Transcriptional Regulators Hif3a And Zbtb16 During Fetal Mouse Lung Development
por: Cole, Timothy, et al.
Publicado: (2019)

SUN-746 Thyroid Hormone Receptor Alpha Sumoylation Is Important for the Development of Adipose Tissue
por: Abe, Kiyomi, et al.
Publicado: (2020)

OR11-04 Activatable Glucocorticoid Receptor Agonists As Treatments For The Consequences Of Preterm Birth
por: Dhavan, Rutu S, et al.
Publicado: (2023)

RF03 | PMON297 Connecting Fluctuations in Estrogen Production, Release, and Action with Hormone-Dependent Gene Expression in Breast Cancers
por: Kim, Hyung Bum, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_e5o0mr9b132865cu89u6tptc46