Cargando…

Cells to Systems Screening for Thyroid Hormone Disrupting Chemicals in the Brain

Precisely timed and regulated thyroid hormone (TH) levels are essential for vertebrate development and metabolism. To detect environmental chemicals that disrupt TH action, we developed an integrated luciferase reporter cell line in rat pituitary GH3 cells that is TH responsive through activation of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Furlow, J David, Mengeling, Brenda J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Endocrine Disruption
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090247/ http://dx.doi.org/10.1210/jendso/bvab048.991

Ejemplares similares

Perchlorate and Nitrate Treatments Disrupt the Endoderm and Thyroid Development Through Epigenetic Mechanisms
por: Serrano-Nascimento, Caroline
Publicado: (2021)

OR23-1 Transgenerational Effects of Endocrine Disrupting Chemicals on Pubertal Timing through Epigenetic Reprogramming of the Hypothalamus
por: Lopez Rodriguez, David, et al.
Publicado: (2019)

MON-035 Aldosterone Secretion in a Human Adrenal Cell Line Is Enhanced by the Endocrine-Disrupting Chemical Di-(2-Ethylhexyl) Phthalate (DEHP)
por: Schupbach, Chad, et al.
Publicado: (2019)

OR23-6 The Impact of PBDE Exposure, Fetal Sex, and Gestational Day on Thyroid Hormone Regulation in the Placenta
por: Ruis, Matthew, et al.
Publicado: (2019)

Disruption of Estrogenic and Androgenic Bioactivities in Human Fetuses Exposed to Maternal Smoking
por: Talia, Chiara, et al.
Publicado: (2021)

ODP276 THYROID CANCER CELLS ARE MORE RESISTANT THAN NORMAL CELLS TO BISPHENOL-A CYTOTOXIC EFFECT
por: Sterian Ward, Laura, et al.
Publicado: (2022)

ODP272 ROUNDUP IS AN IMPORTANT DISRUPTOR THAT CAUSES PROLIFERATIVE EFFECTS ON NORMAL AND ON CANCER THYROID CELLS
por: Ward, Laura Sterian, et al.
Publicado: (2022)

A Novel Peptide Antagonist of the Human Growth Hormone Receptor
por: Basu, Reetobrata None, et al.
Publicado: (2021)

SAT433 Improving The Risk Assessment Procedures For Endocrine Disrupting Chemicals Affecting Thyroid Homeostasis: A Scoping Study
por: La Motta, Concettina
Publicado: (2023)

The Association of the Polychlorinated Biphenyl Class of Endocrine Disruptors With Polycystic Ovary Syndrome and Thyroid Dysfunction
por: Brennan, Edwina, et al.
Publicado: (2021)

Improvements in Long-Term Appetite-Regulating Hormones in Response to a Combined Lifestyle Intervention for Obesity
por: Kuckuck, Susanne
Publicado: (2021)

MON-LB007 Incidence and Characteristics of Thyroid and Pituitary Dysfunction in Patients Treated with Immunotherapy
por: Casey, Caoimhe, et al.
Publicado: (2019)

MON-LB006 Glucocorticoid Biosynthetic Pathway Analysis Divulges the Susceptibility of Adrenal Gland against EDCs In Vivo by Novel Approach Uncovering Endocrine Disruption Mechanism
por: Ahmad, Shahzad, et al.
Publicado: (2019)

MON-030 Non-Target Assessment of Contributory Chemicals and In Vitro Assessment of Molecular Mechanisms of Indoor House Dust Extract-Induced Adipogenesis in 3T3-L1 Cells
por: Kassotis, Christopher, et al.
Publicado: (2019)

RF22 | PMON10 Exposure to a Real Life Environmental Chemical Mixture Alters the Metabolite Profile in the Plasma of Sheep: An Untargeted Metabolomics Study.
por: Evans, Neil, et al.
Publicado: (2022)

Protocol Based Standardized Endocrinological Evaluation of Children With Traumatic Brain Injury: A QI Initiative
por: Bhat, Jayalakshmi Narayan, et al.
Publicado: (2021)

RF22 | PMON04 Sex- and Dose-Dependent Effects of In Utero Endocrine Disruptor Exposure on Offspring Behavior and Brain Monoamines
por: MohanKumar, Sheba, et al.
Publicado: (2022)

SAT447 Gaps In Care: Endocrine-disrupting Chemicals And Metabolic Disease Management Guidelines
por: Obeid, Michele, et al.
Publicado: (2023)

MON-LB009 Renin Angiotensin Aldosterone System Inactivation in Postural Orthostatic Tachycardia Syndrome
por: Kumar, Vishak, et al.
Publicado: (2019)

Bisphenols effects on Granulosa Cell-Cell Communication
por: Sabry, Reem, et al.
Publicado: (2021)

RF22 | PMON09 BPA and BPF, but not BPS, alter pro- and anti-apoptotic transcript levels in granulosa cells, affecting cell viability.
por: Favetta, Laura, et al.
Publicado: (2022)

Hyperthermia as a Steroidogenic Inhibitor of Adrenodortical Cells, an Adrenal Sparing Treatment for Primary Aldosteronism?
por: Donlon, Padraig T, et al.
Publicado: (2021)

LBSUN310 Developmental Programming: Gestational Bpa Treatment Leads To Pancreatic Beta Cell Compromise
por: Ciarelli, Joseph, et al.
Publicado: (2022)

ODP622 A Case of a Rare Steroid Cell Tumor in a Patient with PCOS
por: Elsheikh, Sahar, et al.
Publicado: (2022)

Bisacodyl in Stimulant Laxatives Can Induce Estrogen Agonist/Antagonist Activity in Breast Cancer Cells in Culture
por: Ngo, Lynda, et al.
Publicado: (2021)

MON-039 Lactotrope Cells and Chloride Toxicity: What about a Possible More General Mechanism?
por: Sartor, Pierre
Publicado: (2019)

MON-034 Novel Estrogen Activity and Gene Regulation Induced by Personal Care Products in Breast Cancer Cells
por: Crease, Keturah, et al.
Publicado: (2019)

OR23-3 Differential Effects of Chronic Exposure to Bisphenol-A on Ion Channel Activity and Expression in Mouse Pancreatic Beta-Cells
por: Nadal, Angel, et al.
Publicado: (2019)

RF22 | PMON05 Parabens Promote Pro-Tumorigenic Effects in Luminal Breast Cancer Cell Lines With Diverse Genetic Ancestry
por: Trevino, Lindsey, et al.
Publicado: (2022)

The Effects of Tert-butyl Hydroquinone (TBHQ) on Estrogen Receptor Alpha (ERα) and Tumor Suppressor Gene p53 in Breast Cancer Cells
por: Pfiffner, Samantha, et al.
Publicado: (2021)

MON-038 The Effects of Isoliquiritigenin (ISL) on the Expression of Estrogen Receptor and Tumor Suppressor Genes BRCA-1 and P53 in Breast Cancer Cells
por: Crone, Michael, et al.
Publicado: (2019)

RF22 | PMON08 The effects of Bisphenol A on miR-21 expression and miR-21 mediated apoptosis in bovine granulosa cells.
por: Sabry, Reem, et al.
Publicado: (2022)

PMON13 The Effects of Perfluorooctanesulfonic Acid (PFOS) on the Expression of Estrogen Receptor Alpha (ERα) and Tumor Suppressor Gene BRCA1 in Breast Cancer Cells
por: Hallman, Erin, et al.
Publicado: (2022)

ODP275 The Effects of Tris(2-Chloroethyl) phosphate (TCEP) on the Expression of Estrogen Receptor Alpha and Tumor Suppressor Gene BRCA-1 in Breast Cancer Cell Lines
por: Pfiffner, Samantha, et al.
Publicado: (2022)

Bisphenol A and S, but Not F, Alter Oxidative Stress Levels in Spermatozoa
por: Nguyen, Mimi, et al.
Publicado: (2021)

OR23-5 A Model “Obesogen”, Tributyltin, Promotes Steatosis in Human Liver Cells by Upregulating Lipogenic Gene Expression as a Consequence of Alterations in Both Genomic and Non-Genomic Signaling
por: Chen, Yue, et al.
Publicado: (2019)

ODP263 A Nonbiased Single-Cell Transcriptomic Analysis of Mouse Mammary Gland after Low Dose/Long Term vs. High Dose/Short Term Exposure to PBDEs
por: Saeki, Kohei, et al.
Publicado: (2022)

PMON212 None-surgical sterilization of female dogs
por: Ko, CheMyong J, et al.
Publicado: (2022)

The Effects of Naphthenic Acids on Tryptophan Metabolism and Peripheral Serotonin Signalling
por: Jamshed, Laiba, et al.
Publicado: (2021)

The Effect of the GH/IGF-1 Axis During Trypanosoma Cruzi Infection
por: Mora-Criollo, Patricia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ocq2jai84kglbl9p6v7ta51a18